Sex and gender: modifiers of health, disease, and medicine

F Mauvais-Jarvis, NB Merz, PJ Barnes, RD Brinton… - The Lancet, 2020 - thelancet.com
Clinicians can encounter sex and gender disparities in diagnostic and therapeutic
responses. These disparities are noted in epidemiology, pathophysiology, clinical …

Endocrine aspects of metabolic dysfunction associated steatotic liver disease (MASLD): Beyond insulin resistance

AL Hutchison, F Tavaglione, S Romeo, M Charlton - Journal of Hepatology, 2023 - Elsevier
While the links between metabolic dysfunction associated steatotic liver disease liver
disease (MASLD) and obesity, insulin resistance are widely appreciated, there are a host of …

Objectives, design and main findings until 2020 from the Rotterdam Study

MA Ikram, G Brusselle, M Ghanbari… - European journal of …, 2020 - Springer
Abstract The Rotterdam Study is an ongoing prospective cohort study that started in 1990 in
the city of Rotterdam, The Netherlands. The study aims to unravel etiology, preclinical …

[HTML][HTML] Non-alcoholic fatty liver disease in women–current knowledge and emerging concepts

PC Eng, R Forlano, T Tan, P Manousou, WS Dhillo… - JHEP Reports, 2023 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a major cause of liver disease worldwide,
affecting up to 30% of adults. Progression to non-alcoholic steatohepatitis (NASH) is a key …

Diosgenin attenuates nonalcoholic hepatic steatosis through the hepatic FXR-SHP-SREBP1C/PPARα/CD36 pathway

S Chen, S Sun, Y Feng, X Li, G Yin, P Liang… - European Journal of …, 2023 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide and
has no approved treatment. The hepatic farnesoid X receptor (FXR) is one of the most …

Organ abnormalities caused by Turner syndrome

SH Yoon, GY Kim, GT Choi, JT Do - Cells, 2023 - mdpi.com
Turner syndrome (TS), a genetic disorder due to incomplete dosage compensation of X-
linked genes, affects multiple organ systems, leading to hypogonadotropic hypogonadism …

The interplay between metabolic dysregulations and non-alcoholic fatty liver disease in women after menopause

R Robeva, D Mladenović, M Vesković, D Hrnčić… - Maturitas, 2021 - Elsevier
The hypoestrogenic period after menopause and associated metabolic imbalance might
facilitate the onset of non-alcoholic fatty liver disease (NAFLD) and its progression. The …

Associations between reproductive and hormone-related factors and risk of nonalcoholic fatty liver disease in a multiethnic population

J Wang, AH Wu, FZ Stanczyk, J Porcel… - Clinical …, 2021 - Elsevier
Background & Aims Despite apparent differences between men and women in the
prevalence and incidence of nonalcoholic fatty liver disease (NAFLD), there are limited …

Non-alcoholic fatty liver disease through the female lifespan: the role of sex hormones

K Pafili, SA Paschou, E Armeni, SA Polyzos… - Journal of …, 2022 - Springer
The prevalence of non-alcoholic fatty liver disease (NAFLD) differs between various stages
of the female lifespan. The aim of this review is to summarize current evidence on the …

Association of hysterectomy with nonalcoholic fatty liver disease among US women

S Jin, S Li, P Fang, C Pan, S Huang - Lipids in Health and Disease, 2024 - Springer
Background A postmenopausal rise in the rates of nonalcoholic fatty liver disease (NAFLD)
has been reported in women. This study thus sought to further probe the association of …