MRI quantification of non‐Gaussian water diffusion by kurtosis analysis

JH Jensen, JA Helpern - NMR in Biomedicine, 2010 - Wiley Online Library
Quantification of non‐Gaussianity for water diffusion in brain by means of diffusional kurtosis
imaging (DKI) is reviewed. Diffusional non‐Gaussianity is a consequence of tissue structure …

MR diffusion kurtosis imaging for neural tissue characterization

EX Wu, MM Cheung - NMR in Biomedicine, 2010 - Wiley Online Library
In conventional diffusion tensor imaging (DTI), water diffusion distribution is described as a
2nd‐order three‐dimensional (3D) diffusivity tensor. It assumes that diffusion occurs in a free …

Parkinson disease: diagnostic utility of diffusion kurtosis imaging

JJ Wang, WY Lin, CS Lu, YH Weng, SH Ng, CH Wang… - Radiology, 2011 - pubs.rsna.org
Purpose To examine the usefulness of diffusion kurtosis imaging for the diagnosis of
Parkinson disease (PD). Materials and Methods Examinations were performed with the …

Thalamus and cognitive impairment in mild traumatic brain injury: a diffusional kurtosis imaging study

EJ Grossman, Y Ge, JH Jensen, JS Babb… - Journal of …, 2012 - liebertpub.com
Conventional imaging is unable to detect damage that accounts for permanent cognitive
impairment in patients with mild traumatic brain injury (mTBI). While diffusion tensor imaging …

Towards better MR characterization of neural tissues using directional diffusion kurtosis analysis

ES Hui, MM Cheung, L Qi, EX Wu - Neuroimage, 2008 - Elsevier
MR diffusion kurtosis imaging (DKI) was proposed recently to study the deviation of water
diffusion from Gaussian distribution. Mean kurtosis, the directionally averaged kurtosis, has …

Does diffusion kurtosis imaging lead to better neural tissue characterization? A rodent brain maturation study

MM Cheung, ES Hui, KC Chan, JA Helpern, L Qi… - Neuroimage, 2009 - Elsevier
Diffusion kurtosis imaging (DKI) can be used to estimate excess kurtosis, which is a
dimensionless measure for the deviation of water diffusion profile from Gaussian distribution …

Advances in microstructural diffusion neuroimaging for psychiatric disorders

O Pasternak, S Kelly, VJ Sydnor, ME Shenton - Neuroimage, 2018 - Elsevier
Understanding the neuropathological underpinnings of mental disorders such as
schizophrenia, major depression, and bipolar disorder is an essential step towards the …

[HTML][HTML] Performances of diffusion kurtosis imaging and diffusion tensor imaging in detecting white matter abnormality in schizophrenia

J Zhu, C Zhuo, W Qin, D Wang, X Ma, Y Zhou, C Yu - NeuroImage: Clinical, 2015 - Elsevier
Diffusion kurtosis imaging (DKI) is an extension of diffusion tensor imaging (DTI), exhibiting
improved sensitivity and specificity in detecting developmental and pathological changes in …

Evaluation of diffusion kurtosis imaging in ex vivo hypomyelinated mouse brains

ND Kelm, KL West, RP Carson, DF Gochberg, KC Ess… - Neuroimage, 2016 - Elsevier
Diffusion tensor imaging (DTI), diffusion kurtosis imaging (DKI), and DKI-derived white
matter tract integrity metrics (WMTI) were experimentally evaluated ex vivo through …

Diffusion imaging of white matter in schizophrenia: progress and future directions

KH Karlsgodt - Biological psychiatry: cognitive neuroscience and …, 2016 - Elsevier
Diffusion tensor imaging (DTI) is a powerful tool for the in vivo assessment of white matter
microstructure. The application of DTI methodologies to the study of schizophrenia has …