Although many risk factors could have causal association with endometrial cancer, they are
also prone to residual confounding or other biases which could lead to over‐or …

Objective To verify whether hypogonadism represents a risk factor for cardiovascular (CV)
morbidity and mortality and to verify whether testosterone replacement therapy (TRT) …

The impact of estrogen exposure in preventing or treating cardiovascular disease is
controversial. But it is clear that estrogen has important effects on vascular physiology and …

A myriad of physiological processes in mammals are influenced by estrogens and the
estrogen receptors (ERs), ERα and ERβ. As we reviewed previously, given the widespread …

The main estrogens: estradiol, estrone, and their acyl-esters have been studied essentially
related to their classical estrogenic and pharmacologic functions. However, their main effect …

Purpose: Emerging published reports on the association between estrogen receptor 1
(ESR1) genetic variation and cancer susceptibility are inconsistent. This review and meta …

Numerous epidemiological, clinical, and animal studies showed that cardiac function and
manifestation of cardiovascular diseases (CVDs) are different between males and females …

Increasing evidence suggests that sex differences exist in the etiology, presentation,
treatment, and outcome from stroke. The reasons for these sex disparities are becoming …

Context Androgen deficiency is common in men with chronic heart failure (HF) and is
associated with increased morbidity and mortality. Estrogens are formed by the …

Background and Objectives Lifetime risk of Alzheimer disease (AD) dementia is twofold
higher in women compared with men, and low estrogen levels in postmenopause have …