[HTML][HTML] Pharmacological significance of heterocyclic 1H-benzimidazole scaffolds: a review

S Tahlan, S Kumar, B Narasimhan - BMC chemistry, 2019 - Springer
Heterocyclic compounds are inevitable in a numerous part of life sciences. These molecules
perform various noteworthy functions in nature, medication and innovation. Nitrogen …

[HTML][HTML] Structure–activity relationship analysis of benzimidazoles as emerging anti-inflammatory agents: An overview

R Veerasamy, A Roy, R Karunakaran, H Rajak - Pharmaceuticals, 2021 - mdpi.com
A significant number of the anti-inflammatory drugs currently in use are becoming obsolete.
These are exceptionally hazardous for long-term use because of their possible unfavourable …

Benzimidazole: an emerging scaffold for analgesic and anti-inflammatory agents

M Gaba, S Singh, C Mohan - European journal of medicinal chemistry, 2014 - Elsevier
Within the vast range of heterocycles, benzimidazole and its derivatives are found to be
trendy structures employed for discovery of drugs in the field of pharmaceutical and …

[HTML][HTML] A review on the green synthesis of benzimidazole derivatives and their pharmacological activities

M Nardi, NCH Cano, S Simeonov, R Bence, A Kurutos… - Catalysts, 2023 - mdpi.com
Benzimidazoles and their derivatives play an extraordinarily significant role as therapeutic
agents, eg, antiulcer, analgesic, and anthelmintic drugs. The organic synthesis of …

Design, synthesis, molecular docking and in silico ADMET investigations of novel piperidine-bearing cinnamic acid hybrids as potent antimicrobial agents

AR Zala, DP Rajani, P Kumari - Journal of the Iranian Chemical Society, 2023 - Springer
In order to combat microbial infections and to address the issue of multi-drug resistance, a
class of novel piperidine-bearing cinnamic acid hybrids 4a–4l were synthesized and …

[HTML][HTML] Highly functionalized piperidines: Free radical scavenging, anticancer activity, DNA interaction and correlation with biological activity

S Das, CJ da Silva, MM Silva, MDA Dantas… - Journal of advanced …, 2018 - Elsevier
Twenty-five piperidines were studied as potential radical scavengers and antitumor agents.
Quantitative interaction of compounds with ctDNA using spectroscopic techniques was also …

Imidazole-pyrazole hybrids: Synthesis, characterization and in-vitro bioevaluation against α-glucosidase enzyme with molecular docking studies

F Chaudhry, S Naureen, M Ashraf, M Al-Rashida… - Bioorganic …, 2019 - Elsevier
Herein, substituted imidazole-pyrazole hybrids (2a-2n) were prepared via a multi component
reaction employing pyrazole-4-carbaldehydes (1a-1d), ammonium acetate, benzil and …

[HTML][HTML] Antimicrobial Potential of Different Isolates of Chaetomium globosum Combined with Liquid Chromatography Tandem Mass Spectrometry Chemical Profiling

MS Goda, N El-Kattan, MA Abdel-Azeem, KAM Allam… - Biomolecules, 2023 - mdpi.com
The antimicrobial resistance of pathogenic microorganisms against commercial drugs has
become a major problem worldwide. This study is the first of its kind to be carried out in …

Cyanuric chloride promoted various organic transformations

B Banerjee, A Priya, J Kaur, M Kaur… - Synthetic …, 2023 - Taylor & Francis
Cyanuric chloride is regarded as the green source for the in situ generation of hydrochloric
acid. It is a metal-free, eco-friendly, inexpensive, and commercially available organocatalyst …

Preparation, structure and antioxidant property of manganese(II) and zinc(II) complexes with bis(N-ethylbenzimidazol-2-ylmethyl)allylamine

X Xia, L Xia, G Zhang, J Xu, C Wang, Y Wu… - Journal of …, 2020 - Taylor & Francis
Abstract Bis (N-ethylbenzimidazol-2-ylmethyl) allylamine (EtAIDB) and its two
complexes,[Mn (EtAIDB) Cl2](1) and [Zn (EtAIDB) Cl2](2), have been synthesized and …