[HTML][HTML] Nanopore sequencing technology, bioinformatics and applications
Rapid advances in nanopore technologies for sequencing single long DNA and RNA
molecules have led to substantial improvements in accuracy, read length and throughput …
molecules have led to substantial improvements in accuracy, read length and throughput …
Opportunities and challenges in long-read sequencing data analysis
Long-read technologies are overcoming early limitations in accuracy and throughput,
broadening their application domains in genomics. Dedicated analysis tools that take into …
broadening their application domains in genomics. Dedicated analysis tools that take into …
Analytical validity of nanopore sequencing for rapid SARS-CoV-2 genome analysis
Viral whole-genome sequencing (WGS) provides critical insight into the transmission and
evolution of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Long-read …
evolution of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Long-read …
The third revolution in sequencing technology
EL Van Dijk, Y Jaszczyszyn, D Naquin, C Thermes - Trends in Genetics, 2018 - cell.com
Forty years ago the advent of Sanger sequencing was revolutionary as it allowed complete
genome sequences to be deciphered for the first time. A second revolution came when next …
genome sequences to be deciphered for the first time. A second revolution came when next …
Performance and application of 16S rRNA gene cycle sequencing for routine identification of bacteria in the clinical microbiology laboratory
DL Church, L Cerutti, A Gürtler, T Griener… - Clinical microbiology …, 2020 - Am Soc Microbiol
This review provides a state-of-the-art description of the performance of Sanger cycle
sequencing of the 16S rRNA gene for routine identification of bacteria in the clinical …
sequencing of the 16S rRNA gene for routine identification of bacteria in the clinical …
[HTML][HTML] Nanopore sequencing and assembly of a human genome with ultra-long reads
We report the sequencing and assembly of a reference genome for the human GM12878
Utah/Ceph cell line using the MinION (Oxford Nanopore Technologies) nanopore …
Utah/Ceph cell line using the MinION (Oxford Nanopore Technologies) nanopore …
The Oxford Nanopore MinION: delivery of nanopore sequencing to the genomics community
Nanopore DNA strand sequencing has emerged as a competitive, portable technology.
Reads exceeding 150 kilobases have been achieved, as have in-field detection and …
Reads exceeding 150 kilobases have been achieved, as have in-field detection and …
Towards a genomics-informed, real-time, global pathogen surveillance system
Abstract The recent Ebola and Zika epidemics demonstrate the need for the continuous
surveillance, rapid diagnosis and real-time tracking of emerging infectious diseases. Fast …
surveillance, rapid diagnosis and real-time tracking of emerging infectious diseases. Fast …
Coming of age: ten years of next-generation sequencing technologies
Since the completion of the human genome project in 2003, extraordinary progress has
been made in genome sequencing technologies, which has led to a decreased cost per …
been made in genome sequencing technologies, which has led to a decreased cost per …
Perspectives and benefits of high-throughput long-read sequencing in microbial ecology
Short-read, high-throughput sequencing (HTS) methods have yielded numerous important
insights into microbial ecology and function. Yet, in many instances short-read HTS …
insights into microbial ecology and function. Yet, in many instances short-read HTS …