Mitophagy in cancer: a tale of adaptation
M Vara-Perez, B Felipe-Abrio, P Agostinis - Cells, 2019 - mdpi.com
In the past years, we have learnt that tumors co-evolve with their microenvironment, and that
the active interaction between cancer cells and stromal cells plays a pivotal role in cancer …
the active interaction between cancer cells and stromal cells plays a pivotal role in cancer …
DNA damage and mitochondria in cancer and aging
Age and DNA repair deficiencies are strong risk factors for developing cancer. This is
reflected in the comorbidity of cancer with premature aging diseases associated with DNA …
reflected in the comorbidity of cancer with premature aging diseases associated with DNA …
MCL-1 is a prognostic indicator and drug target in breast cancer
Abstract Analysis of publicly available genomic and gene expression data demonstrates that
MCL1 expression is frequently elevated in breast cancer. Distinct from other pro-survival Bcl …
MCL1 expression is frequently elevated in breast cancer. Distinct from other pro-survival Bcl …
BCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma
J Wang, A Chen, Z Xue, J Liu, Y He, G Liu, Z Zhao… - Cell Death & …, 2023 - nature.com
There is an urgent need for novel diagnostic and therapeutic strategies for patients with
Glioblastoma multiforme (GBM). Previous studies have shown that BCL2 like 13 (BCL2L13) …
Glioblastoma multiforme (GBM). Previous studies have shown that BCL2 like 13 (BCL2L13) …
Understanding MCL1: from cellular function and regulation to pharmacological inhibition
M Sancho, D Leiva, E Lucendo, M Orzáez - The FEBS Journal, 2022 - Wiley Online Library
Myeloid cell leukemia‐1 (MCL1), an antiapoptotic member of the BCL2 family characterized
by a short half‐life, functions as a rapid sensor that regulates cell death and other relevant …
by a short half‐life, functions as a rapid sensor that regulates cell death and other relevant …
Interferon-inducible guanylate binding protein (GBP2) is associated with better prognosis in breast cancer and indicates an efficient T cell response
Background Recently, interferon-inducible guanylate binding protein (GBP2) has been
discussed as a possible control factor in tumor development, which is controlled by p53, and …
discussed as a possible control factor in tumor development, which is controlled by p53, and …
Mitochondria autophagy: a potential target for cancer therapy
YH Qiu, TS Zhang, XW Wang, M Wang… - Journal of drug …, 2021 - Taylor & Francis
Mitophagy is a selective form of macroautophagy in which dysfunctional and damaged
mitochondria can be efficiently degraded, removed and recycled through autophagy …
mitochondria can be efficiently degraded, removed and recycled through autophagy …
BCL2L13: physiological and pathological meanings
F Meng, N Sun, D Liu, J Jia, J Xiao, H Dai - Cellular and Molecular Life …, 2021 - Springer
Abstract BCL2L13 is a BCL2-like protein. It has been discovered for two decades, now on
the way to be a hotspot of research with its physiological and pathological meanings found …
the way to be a hotspot of research with its physiological and pathological meanings found …
A BAG's life: Every connection matters in cancer
The members of the BCL-2 associated athanogene (BAG) family participate in the regulation
of a variety of interrelated physiological processes, such as autophagy, apoptosis, and …
of a variety of interrelated physiological processes, such as autophagy, apoptosis, and …
Immune status, strain background, and anatomic site of inoculation affect mouse papillomavirus (MmuPV1) induction of exophytic papillomas or endophytic …
Papillomaviruses (PVs) induce papillomas, premalignant lesions, and carcinomas in a wide
variety of species. PVs are classified first based on their host and tissue tropism and then …
variety of species. PVs are classified first based on their host and tissue tropism and then …