In the past years, we have learnt that tumors co-evolve with their microenvironment, and that
the active interaction between cancer cells and stromal cells plays a pivotal role in cancer …

Age and DNA repair deficiencies are strong risk factors for developing cancer. This is
reflected in the comorbidity of cancer with premature aging diseases associated with DNA …

Abstract Analysis of publicly available genomic and gene expression data demonstrates that
MCL1 expression is frequently elevated in breast cancer. Distinct from other pro-survival Bcl …

There is an urgent need for novel diagnostic and therapeutic strategies for patients with
Glioblastoma multiforme (GBM). Previous studies have shown that BCL2 like 13 (BCL2L13) …

Myeloid cell leukemia‐1 (MCL1), an antiapoptotic member of the BCL2 family characterized
by a short half‐life, functions as a rapid sensor that regulates cell death and other relevant …

Background Recently, interferon-inducible guanylate binding protein (GBP2) has been
discussed as a possible control factor in tumor development, which is controlled by p53, and …

Mitophagy is a selective form of macroautophagy in which dysfunctional and damaged
mitochondria can be efficiently degraded, removed and recycled through autophagy …

Abstract BCL2L13 is a BCL2-like protein. It has been discovered for two decades, now on
the way to be a hotspot of research with its physiological and pathological meanings found …

The members of the BCL-2 associated athanogene (BAG) family participate in the regulation
of a variety of interrelated physiological processes, such as autophagy, apoptosis, and …

Papillomaviruses (PVs) induce papillomas, premalignant lesions, and carcinomas in a wide
variety of species. PVs are classified first based on their host and tissue tropism and then …