For decades, studies of endocrine-disrupting chemicals (EDCs) have challenged traditional
concepts in toxicology, in particular the dogma of “the dose makes the poison,” because …

Interest in perchlorate as environmental pollutant has increased since 1997, when high
concentrations have been found in the waters of the Colorado River, USA. Perchlorate is …

Perchlorate pharmacology and toxicology studies date back at least 65 years in the peer-
reviewed literature. Repeated studies in animals and humans have demonstrated …

BACKGROUND This biennial review covers developments in environmental mass
spectrometry for emerging environmental contaminants over the period of 2008 to 2009. A …

The developing fetus is likely to be exposed to the same environmental chemicals as the
mother during critical periods of growth and development. The degree of maternal–fetal …

Ion chromatography (IC) plays a crucial role in urine analysis for diverse medical diagnoses.
This paper reviews a comprehensive investigation into urine pretreatment techniques, as …

Background: Perchlorate-induced natrium-iodide symporter (NIS) interference is a well-
recognized thyroid disrupting mechanism. It is unclear, however, whether a chronic low …

Perchlorate, a widespread environmental contaminant originating from various industrial
applications, agricultural practices, and natural sources, poses potential risks to ecosystems …

Perchlorate, ClO4−, interferes with iodide (I−) uptake by the sodium-iodide symporter (NIS)
and thereby affects thyroid hormone production in the body. Studies have reported human …

Perchlorate is a widespread environmental contaminant and potent thyroid hormone
disrupting compound. Despite this, very little is known with regard to the occurrence of this …