Atopic dermatitis endotypes and implications for targeted therapeutics
T Czarnowicki, H He, JG Krueger… - Journal of Allergy and …, 2019 - Elsevier
Recent research advancements indicate that atopic dermatitis (AD) is a complex disease
characterized by different subtypes/phenotypes based on age, disease chronicity, ethnicity …
characterized by different subtypes/phenotypes based on age, disease chronicity, ethnicity …
The immunology of atopic dermatitis and its reversibility with broad-spectrum and targeted therapies
PM Brunner, E Guttman-Yassky, DYM Leung - Journal of Allergy and …, 2017 - Elsevier
Atopic dermatitis (AD), the most common chronic inflammatory skin disease, is driven by
both terminal keratinocyte differentiation defects and strong type 2 immune responses. In …
both terminal keratinocyte differentiation defects and strong type 2 immune responses. In …
[HTML][HTML] Antibiotics, pediatric dysbiosis, and disease
Antibiotics are by far the most common medications prescribed for children. Recent
epidemiological data suggests an association between early antibiotic use and disease …
epidemiological data suggests an association between early antibiotic use and disease …
Early-onset pediatric atopic dermatitis is TH2 but also TH17 polarized in skin
H Esaki, PM Brunner, Y Renert-Yuval… - Journal of Allergy and …, 2016 - Elsevier
Background Atopic dermatitis (AD) affects 15% to 25% of children and 4% to 7% of adults.
Paradigm-shifting discoveries about AD have been based on adult biomarkers, reflecting …
Paradigm-shifting discoveries about AD have been based on adult biomarkers, reflecting …
Associations of wheezing phenotypes in the first 6 years of life with atopy, lung function and airway responsiveness in mid-childhood
J Henderson, R Granell, J Heron, A Sherriff, A Simpson… - Thorax, 2008 - thorax.bmj.com
Background: Patterns of wheezing during early childhood may indicate differences in
aetiology and prognosis of respiratory illnesses. Improved characterisation of wheezing …
aetiology and prognosis of respiratory illnesses. Improved characterisation of wheezing …
The role of the intestinal microbiota in the development of atopic disorders
J Penders, EE Stobberingh, PA Brandt, C Thijs - Allergy, 2007 - Wiley Online Library
The prevalence of atopic diseases, including eczema, allergic rhinoconjunctivitis and
asthma, has increased worldwide, predominantly in westernized countries. Recent …
asthma, has increased worldwide, predominantly in westernized countries. Recent …
Early pediatric atopic dermatitis shows only a cutaneous lymphocyte antigen (CLA)+ TH2/TH1 cell imbalance, whereas adults acquire CLA+ TH22/TC22 cell subsets
T Czarnowicki, H Esaki, J Gonzalez, D Malajian… - Journal of Allergy and …, 2015 - Elsevier
Background Identifying differences and similarities between cutaneous lymphocyte antigen
(CLA)+ polarized T-cell subsets in children versus adults with atopic dermatitis (AD) is …
(CLA)+ polarized T-cell subsets in children versus adults with atopic dermatitis (AD) is …
A short review of human exposure to antibiotics based on urinary biomonitoring
Y Hu, Q Zhu, Y Wang, C Liao, G Jiang - Science of the Total Environment, 2022 - Elsevier
Antibiotics play a role in preventing and treating infectious diseases and also contribute to
other health risks for humans. With the overuse of antibiotics, they are widely distributed in …
other health risks for humans. With the overuse of antibiotics, they are widely distributed in …
[HTML][HTML] The translational revolution in atopic dermatitis: the paradigm shift from pathogenesis to treatment
P Facheris, J Jeffery, E Del Duca… - Cellular & Molecular …, 2023 - nature.com
Atopic dermatitis (AD) is the most common inflammatory skin disease, and it is considered a
complex and heterogeneous condition. Different phenotypes of AD, defined according to the …
complex and heterogeneous condition. Different phenotypes of AD, defined according to the …
[HTML][HTML] Patterns of early-life gut microbial colonization during human immune development: an ecological perspective
I Laforest-Lapointe, MC Arrieta - Frontiers in immunology, 2017 - frontiersin.org
Alterations in gut microbial colonization during early life have been reported in infants that
later developed asthma, allergies, type 1 diabetes, as well as in inflammatory bowel disease …
later developed asthma, allergies, type 1 diabetes, as well as in inflammatory bowel disease …