There is increasing evidence that some neuronal death after brain ischaemia is mediated by
the action of cysteine-requiring aspartate-directed proteases (caspases), the proteases …

Some studies have provided evidence that delayed death of hippocampal CA1 neurons in
transient global ischemia occurs by classical apoptosis. Recently, translocation of synaptic …

The evolution of brain infarcts during permanent occlusion of the middle cerebral artery
(MCA) was studied in mice using multiparametric imaging techniques. Regional protein …

Cerebral ischemia triggers a multitude of pathophysiological and biochemical events that
separately affect the evolution of focal ischemia and, therefore, stroke treatment should …

The mechanism of neuronal death in brain ischaemia remains unclear. Morphology,
terminal transferase‐mediated dUTP‐digoxigenin nick end‐labelling (TUNEL) and …

The generally accepted concept that astrocytes are highly resistant to hypoxic/ischemic
conditions has been challenged by an increasing amount of data. Considering the …

An approach combining reperfusion mediated by thrombolytics with pharmacological
neuroprotection aimed at inhibiting the physiopathological disorders responsible for …

Avenanthramides are a group of phenolic alkaloids that have been shown to have anti-
inflammatory, anti-oxidant, anti-atherogenic, and vasodilation effects. The aim of the present …

Background and Purpose—Neuroprotection studies have demonstrated the involvement of
opioids in ischemia, and we have previously demonstrated alterations in Bmax of …

In experimental models of cerebral ischemia, cells within the damaged territory die by
necrosis and by apoptosis that contributes to the expansion of the insult. Apoptotic …