Drug development is a very costly and lengthy process, while repositioned or repurposed
drugs could be brought into clinical practice within a shorter time-frame and at a much …

The field of genomics has entered a new era in which the ability to identify genetic variants
that impact complex human traits and disease in an unbiased fashion using genome-wide …

“A Mathematical Theory of Communication” was published in 1948 by Claude Shannon to
address the problems in the field of data compression and communication over (noisy) …

Detecting and visualizing nonlinear interactive effects of Single Nucleotide Polymorphisms
(SNPs) or epistatic interactions are important topics of signal processing having great …

Background With the development of high-throughput genotyping and sequencing
technology, there are growing evidences of association with genetic variants and complex …

Since its introduction nearly two decades ago, transfer entropy has contributed to an
improved understanding of cause-and-effect relationships in coupled dynamical systems …

Use of information theory can be an alternative statistical approach to detect genome
regions and candidate genes that are associated with livestock traits. The aim of this study …

The availability of high-density single nucleotide polymorphisms (SNPs) data has made the
human genetic association studies possible to identify common and rare variants underlying …

The study of gene-based genetic associations has gained conceptual popularity recently.
Biologic insight into the etiology of a complex disease can be gained by focusing on genes …

Abstract Information theory is a branch of mathematics that overlaps with communications,
biology, and medical engineering. Entropy is a measure of uncertainty in the set of …