We study the effect of the organic co-solute trimethylamine N-oxide (TMAO) on the volume
phase transition of microgel particles made from poly (N-isopropylacrylamide)(PNIPAM) …

We have performed atomistic molecular dynamics simulations to study the solvation
characteristics of model spheres for low concentrations of urea and hydroxyectoine in …

Trimethylamine-N-oxide (TMAO) and urea are commonly produced in many extremophilic
microorganisms that live in harsh environments. In view of high temperature, high pressure …

Osmolytes are a class of small organic molecules that shift the protein folding equilibrium.
For this reason, they are accumulated by organisms under environmental stress and find …

We describe the development and implementation of a quasi-equilibrium hydration shell
model of biomolecular solvation with adaptive boundaries. Applying the model to …