Pathogen recognition by C-type lectin receptors (CLRs) expressed by dendritic cells is
important not only for antigen presentation, but also for the induction of appropriate adaptive …

Fungi, usually present as commensals, are a major cause of opportunistic infections in
immunocompromised patients. Such infections, if not diagnosed or treated properly, can …

Pathogenic fungi cause a wide range of syndromes in immune-competent and immune-
compromised individuals, with life-threatening disease primarily seen in humans with …

Histoplasma capsulatum, an environmental fungus, is the most common endemic pulmonary
mycosis in the USA. Disease is most frequently observed in immunocompromised patients …

Life-threatening fungal infections have risen sharply in recent years, owing to the advances
and intensity of medical care that may blunt immunity in patients. This emerging crisis has …

Several spleen tyrosine kinase–coupled C-type lectin receptors (CLRs) have emerged as
important pattern recognition receptors for infectious danger. Because encounter with …

Fungi are adept at changing their cell shape and developmental program in response to
signals in their surroundings. Here we focus on a group of evolutionarily related fungal …

Phaeohyphomycosis is a group of severe infections caused by dematiaceous fungi. We
previously identified CARD9 deficiencies in four Chinese patients with phaeohyphomycosis …

The fungal pathogen Histoplasma capsulatum causes respiratory and disseminated
disease, even in immunocompetent hosts. In contrast to opportunistic pathogens, which are …

Th17 cells are characterized as preferential producer of interleukins including IL-17A, IL-
17F, IL-21 and IL-22. Corresponding receptors of these cytokines are expressed on number …