[HTML][HTML] A concise review on potential cancer biomarkers and advanced manufacturing of smart platform-based biosensors for early-stage cancer diagnostics

A Roberts, S Gandhi - Biosensors and Bioelectronics: X, 2022 - Elsevier
Advanced diagnostic technologies for early-stage detection of cancer are essential for
proper management and guided therapeutics to increase chances of survival for patients …

Self-assembled chitosan polymer intercalating peptide functionalized gold nanoparticles as nanoprobe for efficient imaging of urokinase plasminogen activator …

D Shahdeo, V Kesarwani, D Suhag, J Ahmed… - Carbohydrate …, 2021 - Elsevier
Targeting cell surface receptors for specific drug delivery in cancer has garnered lot of
attention. Urokinase plasminogen activator receptor (uPAR), a surface biomarker, is …

B cell epitope mapping: The journey to better vaccines and therapeutic antibodies

AJ De Leon, MC Tjiam, Y Yu - … et Biophysica Acta (BBA)-General Subjects, 2024 - Elsevier
B-cell epitope mapping is an approach that can identify and characterise specific antigen
binding sites of B-cell receptors and secreted antibodies. The ability to determine the …

Graphene nanosheets as an electric mediator for ultrafast sensing of urokinase plasminogen activator receptor-A biomarker of cancer

A Roberts, PP Tripathi, S Gandhi - Biosensors and Bioelectronics, 2019 - Elsevier
Fluorine doped tin oxide (FTO) electrochemical immunosensor has been developed for
rapid detection of urokinase type plasminogen activator receptor (uPAR)-a biomarker for …

Polymeric biocompatible iron oxide nanoparticles labeled with peptides for imaging in ovarian cancer

D Shahdeo, A Roberts, V Kesarwani… - Bioscience …, 2022 - portlandpress.com
Compared with other nanomaterials, surface-modified iron oxide nanoparticles (IONPs)
have gained attraction for cancer therapy applications due to its low toxicity, and long …

Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cancer cells

M Van Veen, E Matas-Rico, K van de Wetering… - Elife, 2017 - elifesciences.org
The urokinase receptor (uPAR) is a glycosylphosphatidylinositol (GPI)-anchored protein that
promotes tissue remodeling, tumor cell adhesion, migration and invasion. uPAR mediates …

Crystal structure and cellular functions of uPAR dimer

S Yu, Y Sui, J Wang, Y Li, H Li, Y Cao, L Chen… - Nature …, 2022 - nature.com
Receptor dimerization of urokinase-type plasminogen activator receptor (uPAR) was
previously identified at protein level and on cell surface. Recently, a dimeric form of mouse …

Urokinase plasminogen activator receptor-mediated targeting of a stable nanocomplex coupled with specific peptides for imaging of cancer

D Shahdeo, AB Chandra, S Gandhi - Analytical Chemistry, 2021 - ACS Publications
Targeting peptides are a promising tool for early diagnosis and therapy of cancer.
Overexpression of urokinase plasminogen activator receptor (uPAR) leads to the …

Intersection of Coagulation and Fibrinolysis by the Glycosylphosphatidylinositol (GPI)-Anchored Serine Protease Testisin

MS Buzza, NR Pawar, AA Strong… - International Journal of …, 2023 - mdpi.com
Hemostasis is a delicate balance between coagulation and fibrinolysis that regulates the
formation and removal of fibrin, respectively. Positive and negative feedback loops and …

New trends in biosensor development for pesticide detection

NS Shrikrishna, S Mahari, N Abbineni… - … in Agriculture: Recent …, 2021 - Springer
Increased use of pesticides globally has led to harmful consequences on the environment,
livestock, animals, as well as humans. Hence, its detection in animal feed, vegetables …