The most recent and non-invasive approach for studying early-stage biomarkers is liquid
biopsy. This implies the extraction and analysis of non-solid biological tissues (serum …

Epigenetic changes in DNA methylation contribute to the development of many diseases,
including cancer. In glioblastoma multiforme, the most prevalent primary brain cancer and …

Glioblastoma (GBM) is the most common primary tumor of the central nervous system.
Arising from neuroepithelial glial cells, GBM is characterized by invasive behavior, extensive …

Simple Summary Despite a substantial increase in publications in recent years, liquid biopsy
from blood, cerebrospinal fluid (CSF), and other body fluids is usually not routinely used in …

Brain tumours are a serious concern among both physicians and patients. The most feared
brain tumour is glioblastoma (GBM) due to its heterogeneous histology, substantial invasive …

After chemoradiotherapy for glioblastoma, pseudoprogression can occur and must be
distinguished from true progression to correctly manage glioblastoma treatment and follow …

Gliomas are a heterogenous group of central nervous system tumors with different outcomes
and different therapeutic needs. Glioblastoma, the most common subtype in adults, has a …

Gliomas are the most common type of malignant brain tumor and are characterized by a
plethora of heterogeneous molecular alterations. Current treatments require the emergence …

Background Although major advances have been made in the histopathological diagnosis
of high-grade astrocytoma (HGA), methods for effective and noninvasive diagnosis remain …

The TERT promoter (pTERT) mutations, C228T and C250T, play a significant role in
malignant transformation by telomerase activation, oncogenesis and immortalisation of cells …