Triple-negative breast cancer: a brief review about epidemiology, risk factors, signaling pathways, treatment and role of artificial intelligence
NM Almansour - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
Triple-negative breast cancer (TNBC) is a kind of breast cancer that lacks estrogen,
progesterone, and human epidermal growth factor receptor 2. This cancer is responsible for …
progesterone, and human epidermal growth factor receptor 2. This cancer is responsible for …
Newly developed targeted therapies against the androgen receptor in triple-negative breast cancer: A review
Among different types of breast cancers (BC), triple-negative BC (TNBC) amounts to 15% to
20% of breast malignancies. Three principal characteristics of TNBC cells are (i) extreme …
20% of breast malignancies. Three principal characteristics of TNBC cells are (i) extreme …
The impact of site-specific digital histology signatures on deep learning model accuracy and bias
Abstract The Cancer Genome Atlas (TCGA) is one of the largest biorepositories of digital
histology. Deep learning (DL) models have been trained on TCGA to predict numerous …
histology. Deep learning (DL) models have been trained on TCGA to predict numerous …
Clinicopathologic characteristics and prognosis of ERBB2-low breast cancer among patients in the National Cancer Database
Importance Given conflicting results regarding the prognosis of erb-b2 receptor tyrosine
kinase 2 (ERBB2; formerly HER2 or HER2/neu)–low breast cancer, a large-scale, nationally …
kinase 2 (ERBB2; formerly HER2 or HER2/neu)–low breast cancer, a large-scale, nationally …
Immunotherapy for metastatic triple negative breast cancer: current paradigm and future approaches
V Geurts, M Kok - Current Treatment Options in Oncology, 2023 - Springer
Opinion statement In approximately 15–20% of the patients diagnosed with breast cancer, it
comprises the triple negative (TN) subtype, which until recently lacked targets for specific …
comprises the triple negative (TN) subtype, which until recently lacked targets for specific …
Disparities in breast cancer
VF Grabinski, OW Brawley - Obstetrics and Gynecology …, 2022 - obgyn.theclinics.com
In the western world, breast cancer is the most common lethal cancer in women and the
second leading cause of cancer death behind lung cancer. 1 The American Cancer Society …
second leading cause of cancer death behind lung cancer. 1 The American Cancer Society …
Triple negative breast cancer: Immunogenicity, tumor microenvironment, and immunotherapy
S Loizides, A Constantinidou - Frontiers in genetics, 2023 - frontiersin.org
Triple negative breast cancer (TNBC) is a biologically diverse subtype of breast cancer
characterized by genomic and transcriptional heterogeneity and exhibiting aggressive …
characterized by genomic and transcriptional heterogeneity and exhibiting aggressive …
Clinical trials of immunotherapy in triple-negative breast cancer
Purpose Immunotherapy has started to transform the treatment of triple-negative breast
cancer (TNBC), in part due to the unique immunogenicity of this breast cancer subtype. This …
cancer (TNBC), in part due to the unique immunogenicity of this breast cancer subtype. This …
Triple-negative breast cancer: epidemiology, molecular mechanisms, and modern vaccine-based treatment strategies
Long-standing scarcity of efficacious treatments and tumor heterogeneity have contributed to
triple-negative breast cancer (TNBC), a subtype with a poor prognosis and aggressive …
triple-negative breast cancer (TNBC), a subtype with a poor prognosis and aggressive …
Biomimetic multifunctional nanodrugs enable regulating abnormal tumor metabolism and amplifying PDT-induced immunotherapy for synergistically enhanced tumor …
Y Liu, H Wu, S Wang, X Zhang, L Gong, C Xiao, C Liu… - Materials Today, 2023 - Elsevier
Aberrant tumor metabolic activities not only promote the aggressiveness and proliferation of
tumor cells in the harsh microenvironment in vivo, but also contribute to immune cell …
tumor cells in the harsh microenvironment in vivo, but also contribute to immune cell …