Polyphenols and mitochondria: an update on their increasingly emerging ROS-scavenging independent actions
C Sandoval-Acuña, J Ferreira, H Speisky - Archives of biochemistry and …, 2014 - Elsevier
Polyphenols, ubiquitously present in fruits and vegetables, have been traditionally viewed
as antioxidant molecules. Such contention emerged, mainly from their well established in …
as antioxidant molecules. Such contention emerged, mainly from their well established in …
Natural drugs as a treatment strategy for cardiovascular disease through the regulation of oxidative stress
X Chang, T Zhang, W Zhang, Z Zhao… - Oxidative Medicine and …, 2020 - Wiley Online Library
Oxidative stress (OS) refers to the physiological imbalance between oxidative and
antioxidative processes leading to increased oxidation, which then results in the …
antioxidative processes leading to increased oxidation, which then results in the …
Natural compounds modulating mitochondrial functions
L Gibellini, E Bianchini, S De Biasi… - Evidence‐Based …, 2015 - Wiley Online Library
Mitochondria are organelles responsible for several crucial cell functions, including
respiration, oxidative phosphorylation, and regulation of apoptosis; they are also the main …
respiration, oxidative phosphorylation, and regulation of apoptosis; they are also the main …
Cardiovascular disease: a target for the pharmacological effects of quercetin
J Guillermo Gormaz, S Quintremil… - Current topics in …, 2015 - ingentaconnect.com
Quercetin, a prominent dietary antioxidant present in vegetables, especially onions, fruits,
highlighting apples and berries, wine and tea, belongs to a group of plant derived …
highlighting apples and berries, wine and tea, belongs to a group of plant derived …
Neferine protected cardiomyocytes against hypoxia/oxygenation injury through SIRT1/Nrf2/HO‐1 signaling
C Lu, B Jiang, J Xu, X Zhang… - Journal of Biochemical …, 2023 - Wiley Online Library
Acute myocardial infarction is regarded as myocardial necrosis resulting from myocardial
ischemia/reperfusion (I/R) damage and retains a major cause of mortality. Neferine, which …
ischemia/reperfusion (I/R) damage and retains a major cause of mortality. Neferine, which …
Quercetin protects radiation-induced DNA damage and apoptosis in kidney and bladder tissues of rats
Ionizing radiation (IR) can induce cell damage and cell death through the reactive oxygen
species generated by radiolytic hydrolysis. The present study was aimed to determine the …
species generated by radiolytic hydrolysis. The present study was aimed to determine the …
Quercetin liposomal nanoformulation for ischemia and reperfusion injury treatment
M Ferreira-Silva, C Faria-Silva, MC Carvalheiro… - Pharmaceutics, 2022 - mdpi.com
Ischemia and reperfusion injury (IRI) is a common complication caused by inflammation and
oxidative stress resulting from liver surgery. Current therapeutic strategies do not present the …
oxidative stress resulting from liver surgery. Current therapeutic strategies do not present the …
Milrinone ameliorates ischaemia‐reperfusion injury in experimental testicular torsion/detorsion rat model
This experimental study aims to evaluate the efficacy of milrinone against ischaemia‐
reperfusion injury due to testicular torsion/detorsion. Group 1 was defined as the control …
reperfusion injury due to testicular torsion/detorsion. Group 1 was defined as the control …
Hepatotoxicity and renal toxicity induced by radiation and the protective effect of quercetin in male albino rats
Purpose Although radiation is one of the basic methods commonly used in cancer treatment,
it inevitably enters the field of treatment in healthy tissues and is adversely affected by the …
it inevitably enters the field of treatment in healthy tissues and is adversely affected by the …
Effect of chemotherapy exposure prior to pregnancy on fetal brain tissue and the potential protective role of quercetin
Cyclophosphamide (CYC) and doxorubicin (DOX) are among the most effective and widely
used anticancer chemotherapeutic drugs. Potential chemopreventive and chemotherapeutic …
used anticancer chemotherapeutic drugs. Potential chemopreventive and chemotherapeutic …