BK polyomavirus and the transplanted kidney: immunopathology and therapeutic approaches

C Lamarche, J Orio, S Collette, L Senécal… - …, 2016 - journals.lww.com
BK polyomavirus is ubiquitous, with a seropositivity rate of over 75% in the adult population.
Primary infection is thought to occur in the respiratory tract, but asymptomatic BK virus …

Regulation of polyomavirus transcription by viral and cellular factors

JF Yang, J You - Viruses, 2020 - mdpi.com
Polyomavirus infection is widespread in the human population. This family of viruses
normally maintains latent infection within the host cell but can cause a range of human …

Identification of MW polyomavirus, a novel polyomavirus in human stool

EA Siebrasse, A Reyes, ES Lim, G Zhao… - Journal of …, 2012 - Am Soc Microbiol
We have discovered a novel polyomavirus present in multiple human stool samples. The
virus was initially identified by shotgun pyrosequencing of DNA purified from virus-like …

MicroRNA 373 facilitates the replication of porcine reproductive and respiratory syndrome virus by its negative regulation of type I interferon induction

J Chen, X Shi, X Zhang, A Wang, L Wang… - Journal of …, 2017 - Am Soc Microbiol
MicroRNAs (miRNAs) play an important role in the regulation of immune responses.
Previous studies have indicated that dysregulating the miRNAs leads to the …

Rearrangement in the hypervariable region of JC polyomavirus genomes isolated from patient samples and impact on transcription factor-binding sites and disease …

MP Wilczek, AMC Pike, SE Craig, MS Maginnis… - International Journal of …, 2022 - mdpi.com
JC polyomavirus (JCPyV) is the causative agent of the fatal, incurable, neurological disease,
progressive multifocal leukoencephalopathy (PML). The virus is present in most of the adult …

Human polyomaviruses: the battle of large and small tumor antigens

CF Baez, R Brandão Varella… - Virology: research …, 2017 - journals.sagepub.com
About 40 years ago, the large and small tumor antigens (LT-Ag and sT-Ag) of the
polyomavirus (PyVs) simian vacuolating virus 40 have been identified and characterized. To …

Polyomavirus persistence

MJ Imperiale, M Jiang - Annual review of virology, 2016 - annualreviews.org
Mammalian polyomaviruses are characterized by establishing persistent infections in
healthy hosts and generally causing clinical disease only in hosts whose immune systems …

[HTML][HTML] BK polyomavirus microRNA expression and sequence variation in polyomavirus-associated nephropathy

E Virtanen, H Seppälä, I Helanterä, P Laine… - Journal of Clinical …, 2018 - Elsevier
Background BK polyomavirus (BKPyV) infection is a common asymptomatic viral infection in
the general population. Severe complications are seen in immunocompromised individuals …

Single-Cell Transcriptome Identifies the Renal Cell Type Tropism of Human BK Polyomavirus

F Yang, X Chen, H Zhang, GD Zhao, H Yang… - International Journal of …, 2023 - mdpi.com
BK polyomavirus (BKPyV) infection is the main factor affecting the prognosis of kidney
transplant recipients, as no antiviral agent is yet available. A better understanding of the …

Database and statistical analyses of transcription factor binding sites in the non-coding control region of JC virus

K Nakamichi, T Shimokawa - Viruses, 2021 - mdpi.com
JC virus (JCV), as an archetype, establishes a lifelong latent or persistent infection in many
healthy individuals. In immunocompromised patients, prototype JCV with variable mutations …