Hyaluronic acid hydrogels crosslinked in physiological conditions: Synthesis and biomedical applications

LA Pérez, R Hernández, JM Alonso, R Pérez-González… - Biomedicines, 2021 - mdpi.com
Hyaluronic acid (HA) hydrogels display a wide variety of biomedical applications ranging
from tissue engineering to drug vehiculization and controlled release. To date, most of the …

[HTML][HTML] Endothelial progenitor cell-derived small extracellular vesicles for myocardial angiogenesis and revascularization

MT Al-Omar, MT Alnajjar, ZT Ahmed… - Journal of Clinical …, 2022 - ncbi.nlm.nih.gov
Background: Endothelial progenitor cells (EPCs) have been well-studied for their
differentiation potential and paracrine activity in vitro and in experimental animal studies …

Fabrication of versatile dynamic hyaluronic acid-based hydrogels

W Shi, B Hass, MA Kuss, H Zhang, S Ryu, D Zhang… - Carbohydrate …, 2020 - Elsevier
In this study, an injectable and self-healing hydrogel based on the boronic ester dynamic
covalent bond between phenylboronic acid modified hyaluronic acid (HA-PBA) and the …

Brain microenvironment responsive and pro‐angiogenic extracellular vesicle‐hydrogel for promoting neurobehavioral recovery in type 2 diabetic mice after stroke

Y Jiang, R Wang, C Wang, Y Guo, T Xu… - Advanced …, 2022 - Wiley Online Library
Stroke patients with diabetes have worse neurological outcomes than non‐diabetic stroke
patients, and treatments beneficial for non‐diabetic stroke patients are not necessarily …

Laser‐Assisted Fabrication of Injectable Nanofibrous Cell Carriers

P Nakielski, C Rinoldi, M Pruchniewski, S Pawłowska… - Small, 2022 - Wiley Online Library
The use of injectable biomaterials for cell delivery is a rapidly expanding field which may
revolutionize the medical treatments by making them less invasive. However, creating …

Injectable hydrogel-based nanocomposites for cardiovascular diseases

X Liao, X Yang, H Deng, Y Hao, L Mao… - … in Bioengineering and …, 2020 - frontiersin.org
Cardiovascular diseases (CVDs), including a series of pathological disorders, severely
affect millions of people all over the world. To address this issue, several potential therapies …

Injectable conductive nanocomposite hydrogels for cardiac tissue engineering: Focusing on carbon and metal-based nanostructures

B Pournemati, H Tabesh, A Jenabi, RM Aghdam… - European Polymer …, 2022 - Elsevier
Cardiovascular diseases are the leading cause of death today and a significant public
health problem. Currently, there is no proper treatment for major cardiovascular diseases …

Hyaluronic Acid Facilitates Angiogenesis of Endothelial Colony Forming Cell Combining With Mesenchymal Stem Cell via CD44/ MicroRNA-139-5p Pathway

Y Luo, F Liang, X Wan, S Liu, L Fu, J Mo… - … in bioengineering and …, 2022 - frontiersin.org
Stem cells and progenitor cells have been identified as potential new therapeutic options for
severe limb ischemia to induce angiogenesis, and hyaluronic acid (HA) is commonly …

Nanoparticle–hydrogel system for post-myocardial infarction delivery of microRNA

S Bheri, ME Davis - ACS nano, 2019 - ACS Publications
Effective therapies for cardiac repair and regeneration after myocardial infarction (MI) are
rather limited. Although microRNAs (miRs) are known to play an important role in improving …

Injectable hydrogels for improving cardiac cell therapy—in vivo evidence and translational challenges

C Hoeeg, A Dolatshahi-Pirouz, B Follin - Gels, 2021 - mdpi.com
Cell therapy has the potential to regenerate cardiac tissue and treat a variety of cardiac
diseases which are currently without effective treatment. This novel approach to treatment …