Guanine-rich DNA sequences have the propensity to adopt four-stranded tetrahelical G-
quadruplex (G4) structures that are overrepresented in gene promoters. The structural …

Accumulating evidence has linked G-quadruplex structures to a number of biological
processes in vivo, including DNA replication, transcription, and genomic maintenance …

Guanine‐rich nucleic acid sequences able to form four‐stranded structures (G‐
quadruplexes, G4) play key cellular regulatory roles and are considered as promising drug …

New cyanines were prepared by an efficient and practical route with satisfactory overall yield
from low-cost starting materials. The photophysical behavior of the cyanines was …

Cyanine dyes are important chemical modifications of oligonucleotides exhibiting intensive
and stable fluorescence at visible light wavelengths. When Cy3 or Cy5 dye is attached to …

Arene Ru (II) complexes have long been extensively studied as potential inhibitors against
the proliferation of tumor cells, but their behavior against the migration and invasion of tumor …

Functional near-infrared (NIR) fluorophores have played a major role in the recent advances
in bioimaging. However, the optical and physicochemical stabilities of NIR fluorophores in …

G-Quadruplexes (G4s) are ubiquitous nucleic acid folding motifs that exhibit structural
diversity that is dependent on cationic conditions. In this work, we exploit temperature …

Protein arginine methyltransferase 1 (PRMT1) is involved in many biological activities, such
as gene transcription, signal transduction, and RNA processing. Overexpression of PRMT1 …

A time-efficient and eco-conscious microwave methodology was developed and applied to
synthesize a systematic library of pentamethine cyanine dyes and their corresponding …