Becaplermin: recombinant platelet derived growth factor, a new treatment for healing diabetic foot ulcers

JM Embil, MK Nagai - Expert opinion on biological therapy, 2002 - Taylor & Francis
Chronic or non-healing lower extremity ulcerations in diabetics are a significant cause of
morbidity and mortality, and account for a large proportion of the financial burden related to …

Principles of flap prefabrication

RK Khouri, J Upton, WW Shaw - Clinics in plastic surgery, 1992 - Elsevier
Clinical flap prefabrication can be classified according to the basic technique of plastic
surgery used for the prefabrication. There are currently three methods:(1) delay or …

Nano-fibrous scaffold for controlled delivery of recombinant human PDGF-BB

G Wei, Q Jin, WV Giannobile, PX Ma - Journal of Controlled Release, 2006 - Elsevier
The localized and temporally controlled delivery of growth factors is key to achieving optimal
clinical efficacy. In sophisticated tissue engineering strategies, the biodegradable scaffold is …

Formation of new tissue from an arteriovenous loop in the absence of added extracellular matrix

R Mian, WA Morrison, JV Hurley, AJ Penington… - Tissue …, 2000 - liebertpub.com
A major requirement for the microsurgical repair of contour defects of the skin, for example,
following removal of a skin cancer on the face, is a mass of vascularised subcutaneous …

Cartilage engineered in predetermined shapes employing cell transplantation on synthetic biodegradable polymers

WS Kim, JP Vacanti, L Cima, D Mooney… - Plastic and …, 1994 - journals.lww.com
Cartilage is often used as structural support tissue for cosmetic repair in plastic and
reconstructive surgery. We describe the efficacy of a new approach for the generation of …

Tissue engineering skin flaps: which vascular carrier, arteriovenous shunt loop or arteriovenous bundle, has more potential for angiogenesis and tissue generation?

Y Tanaka, KC Sung, A Tsutsumi, S Ohba… - Plastic and …, 2003 - journals.lww.com
This study was designed to clarify which vascular carrier, the arteriovenous shunt loop or the
arteriovenous bundle, has more potential as a vascular carrier for an artificial skin flap in …

New murine model of spontaneous autologous tissue engineering, combining an arteriovenous pedicle with matrix materials

KJ Cronin, A Messina, KR Knight… - Plastic and …, 2004 - journals.lww.com
The authors previously described a model of tissue engineering in rats that involves the
insertion of a vascular pedicle and matrix material into a semirigid closed chamber, which is …

Angiogenic growth factor synergism in a murine tissue engineering model of angiogenesis and adipogenesis

JA Rophael, RO Craft, JA Palmer, AJ Hussey… - The American journal of …, 2007 - Elsevier
De novo tissue generation stimulated by three angiogenic growth factors administered in a
factorial design was studied in an in vivo murine tissue engineering chamber. A silicone …

Nonsurgical breast enlargement using an external soft-tissue expansion system

RK Khouri, I Schlenz, BJ Murphy… - Plastic and reconstructive …, 2000 - journals.lww.com
Less than 1 percent of the women interested in having larger breasts elect to have surgical
augmentation mammaplasty with insertion of breast implants. The purpose of this report is to …

Generation of an autologous tissue (matrix) flap by combining an arteriovenous shunt loop with artificial skin in rats: preliminary report

Y Tanaka, A Tsutsumi, DM Crowe, S Tajima… - British journal of plastic …, 2000 - Elsevier
The present experiment was designed to investigate the possibility of prefabricating a tissue
flap in a rat by combining an arteriovenous (AV) shunt loop with artificial skin dermis (AS) …