The therapeutic efficacy of antiretroviral drugs as well as challenges and side effects against
the human immunodeficiency virus is well documented and reviewed. Evidence is available …

Drug impurity and degradation profiling mean the detection, structure elucidation and
quantitative determination of impurities and degradation products in bulk drug materials and …

Degradation studies of drug give insightful information about the intrinsic stability of the
molecule, the possible degradents formed during shelf life and thus, aid in the subsequent …

In the present study, degradation behaviour of abacavir sulfate was evaluated in solution
and solid stress conditions. Solution state studies resulted in formation of eleven …

The present study focused upon the forced degradation behaviour of fosamprenavir (FPV),
an antiretroviral drug. A total of six degradation products (DPs) were separated on a non …

Efavirenz (EFV), an antiretroviral drug, was evaluated for its degradation behaviour in
solution state. A total of twelve degradation products were detected on high performance …

Abstract The current United States Pharmacopeia–National Formulary (USP–NF) includes
more than 250 monographs of fixed dose combinations (FDCs), and some of them need to …

Zidovudine (ZDV) and efavirenz (EFV), which belong to two separate classes of antiretroviral
drugs, viz., NRTI and NNRTI, respectively, were subjected to different stability test conditions …

A mechanism of unusual tandem (MS/MS) fragmentation of protonated species of N-
(triphenyl-λ5-phosphanylidene) derivatives,[M+ H]+ to generate triphenylphosphine oxide …

Human immunodeficiency virus (HIV) is still a major public health issue. While there is still
no cure for HIV infections, the drug treatments have improved with one-size-fits-all becoming …