Bronchopulmonary dysplasia (BPD) is the most common cause of morbidity and mortality in
preterm infants. A key histopathological feature of BPD is stunted late lung development …

The fibroblast growth factor/fibroblast growth factor receptor (FGF/FGFR) signaling system
regulates a variety of biological processes, including embryogenesis, angiogenesis, wound …

Pulmonary endothelial cells (ECs) are an essential component of the gas exchange
machinery of the lung alveolus. Despite this, the extent and function of lung EC …

The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …

Even more than 50 years after its initial description, bronchopulmonary dysplasia (BPD)
remains one of the most important and lifelong sequelae following premature birth …

Bronchopulmonary dysplasia (BPD) is a chronic lung disease commonly seen in preterm
infants, and is triggered by infection, mechanical ventilation, and oxygen toxicity. Among …

The alveolar and vascular developmental arrest in the premature infants poses a major
problem in the management of these infants. Although, with the current management, the …

Background Pulmonary arterial hypertension (PAH) is a fatal disease, with approximately
10% of cases associated with genetic variants. Recent genetic studies have reported …

FGF10, as an FGFR2b-specific ligand, plays a crucial role during cell proliferation, multi-
organ development, and tissue injury repair. The developmental importance of FGF10 has …

The shortage of donor lungs hinders lung transplantation, the only definitive option for
patients with end-stage lung disease. Blastocyst complementation enables the generation of …