Recent developments in machine learning for mass spectrometry

AG Beck, M Muhoberac, CE Randolph… - ACS Measurement …, 2024 - ACS Publications
Statistical analysis and modeling of mass spectrometry (MS) data have a long and rich
history with several modern MS-based applications using statistical and chemometric …

A guide to MALDI imaging mass spectrometry for tissues

JL Moore, G Charkoftaki - Journal of Proteome Research, 2023 - ACS Publications
Imaging mass spectrometry is a well-established technology that can easily and succinctly
communicate the spatial localization of molecules within samples. This review …

Single cell analysis of proteoforms

P Su, MAR Hollas, FA Butun… - Journal of Proteome …, 2024 - ACS Publications
We introduce single cell Proteoform imaging Mass Spectrometry (scPiMS), which realizes
the benefit of direct solvent extraction and MS detection of intact proteins from single cells …

Single Cell mass spectrometry: Towards quantification of small molecules in individual cells

Y Lan, Z Zou, Z Yang - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
Studying cell heterogeneity can provide a deeper understanding of biological activities, but
appropriate studies cannot be performed using traditional bulk analysis methods. The …

Mass‐Guided Single‐Cell MALDI Imaging of Low‐Mass Metabolites Reveals Cellular Activation Markers

JL Cairns, J Huber, A Lewen, J Jung… - Advanced …, 2024 - Wiley Online Library
Single‐cell MALDI mass spectrometry imaging (MSI) of lipids and metabolites> 200 Da has
recently come to the forefront of biomedical research and chemical biology. However, cell …

[HTML][HTML] Novel repurposing of sulfasalazine for the treatment of adrenocortical carcinomas, probably through the SLC7A11/xCT-hsa-miR-92a-3p-OIP5-AS1 network …

C Subramanian, K McNamara, SW Croslow, Y Tan… - Surgery, 2024 - Elsevier
Background Recent multigenomic analysis of adrenocortical carcinomas (ACCs) identified
SLC7A11/xCT as a novel biomarker. The Food and Drug Administration–approved anti …

[引用][C] Exploring Cell Heterogeneity: Applications of Single-probe Single Cell Mass Spectrometry for Subpopulation Analysis

T Nguyen - 2023