Background—Age-related dementia, most commonly caused by Alzheimer disease or
cerebrovascular factors (vascular dementia), is a major public health threat. Chronic arterial …

Aging, hypertension, diabetes, hypoxia/obstructive sleep apnea (OSA), obesity, vitamin
B12/folate deficiency, depression, and traumatic brain injury synergistically promote diverse …

Two decades of epidemiological research shows that silent cerebrovascular disease is
common and is associated with future risk for stroke and dementia. It is the most common …

Higher educational attainment is observationally associated with lower risk of Alzheimer's
disease. However, the biological mechanisms underpinning this association remain unclear …

Metabolic syndrome is a cluster of cardiovascular risk factors defined by the presence of
abdominal obesity, glucose intolerance, hypertension and/or dyslipidemia. It is a major …

Arterial hypertension (HTN) accounts for the largest amount of attributable cardiovascular
(CV) mortality worldwide, and risk stratification in hypertensive patients is of crucial …

Arterial hypertension accounts for the largest amount of attributable cardiovascular mortality
worldwide, and risk stratification in hypertensive patients is of crucial importance to manage …

Background Heightened blood pressure (BP) responses to mental stress predict raised BP
levels over subsequent years, but evidence for associations with incident hypertension is …

In cognitively normal (CN) elderly individuals, white matter hyperintensities (WMH) are
commonly viewed as a marker of cerebral small vessel disease (SVD). SVD is due to …

Objective To test whether elevated blood pressure (BP) relates to gray matter (GM) volume
(GMV) changes in young adults who had not previously been diagnosed with hypertension …