Quantitative susceptibility mapping (QSM): decoding MRI data for a tissue magnetic biomarker

Y Wang, T Liu - Magnetic resonance in medicine, 2015 - Wiley Online Library
In MRI, the main magnetic field polarizes the electron cloud of a molecule, generating a
chemical shift for observer protons within the molecule and a magnetic susceptibility …

Clinical quantitative susceptibility mapping (QSM): biometal imaging and its emerging roles in patient care

Y Wang, P Spincemaille, Z Liu, A Dimov… - Journal of magnetic …, 2017 - Wiley Online Library
Quantitative susceptibility mapping (QSM) has enabled magnetic resonance imaging (MRI)
of tissue magnetic susceptibility to advance from simple qualitative detection of hypointense …

The physics of functional magnetic resonance imaging (fMRI)

RB Buxton - Reports on Progress in Physics, 2013 - iopscience.iop.org
Functional magnetic resonance imaging (fMRI) is a methodology for detecting dynamic
patterns of activity in the working human brain. Although the initial discoveries that led to …

BOLD hemodynamic response function changes significantly with healthy aging

KL West, MD Zuppichini, MP Turner, DK Sivakolundu… - NeuroImage, 2019 - Elsevier
Functional magnetic resonance imaging (fMRI) has been used to infer age-differences in
neural activity from the hemodynamic response function (HRF) that characterizes the blood …

Non-BOLD contrast for laminar fMRI in humans: CBF, CBV, and CMRO2

L Huber, K Uludağ, HE Möller - Neuroimage, 2019 - Elsevier
Functional magnetic resonance imaging (fMRI) using the blood oxygenation level-
dependent (BOLD) contrast indirectly probes neuronal activity changes via evoked cerebral …

The clinical utility of QSM: disease diagnosis, medical management, and surgical planning

S Eskreis‐Winkler, Y Zhang, J Zhang, Z Liu… - NMR in …, 2017 - Wiley Online Library
Quantitative susceptibility mapping (QSM) is an MR technique that depicts and quantifies
magnetic susceptibility sources. Mapping iron, the dominant susceptibility source in the …

Quantitative mapping of cerebral metabolic rate of oxygen (CMRO2) using quantitative susceptibility mapping (QSM)

J Zhang, T Liu, A Gupta, P Spincemaille… - Magnetic resonance …, 2015 - Wiley Online Library
Purpose To quantitatively map cerebral metabolic rate of oxygen () and oxygen extraction
fraction () in human brains using quantitative susceptibility mapping (QSM) and arterial spin …

A review of calibrated blood oxygenation level‐dependent (BOLD) methods for the measurement of task‐induced changes in brain oxygen metabolism

NP Blockley, VEM Griffeth, AB Simon… - NMR in …, 2013 - Wiley Online Library
The dynamics of the blood oxygenation level‐dependent (BOLD) response are dependent
on changes in cerebral blood flow, cerebral blood volume and the cerebral metabolic rate of …

Cerebral oxygen extraction fraction MRI: Techniques and applications

D Jiang, H Lu - Magnetic resonance in medicine, 2022 - Wiley Online Library
The human brain constitutes 2% of the body's total mass but uses 20% of the oxygen. The
rate of the brain's oxygen utilization can be derived from a knowledge of cerebral blood flow …

Measurement of OEF and absolute CMRO2: MRI-based methods using interleaved and combined hypercapnia and hyperoxia

RG Wise, AD Harris, AJ Stone, K Murphy - Neuroimage, 2013 - Elsevier
Blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI)
is most commonly used in a semi-quantitative manner to infer changes in brain activity …