L-asparaginase in the treatment of patients with acute lymphoblastic leukemia
RA Egler, SP Ahuja, Y Matloub - Journal of Pharmacology …, 2016 - journals.sagepub.com
Acute lymphoblastic leukemia (ALL) is a hematologic malignancy that predominantly occurs
in children between 2 and 10 years of age. L-asparaginase is an integral component of …
in children between 2 and 10 years of age. L-asparaginase is an integral component of …
Asparaginase-associated toxicity in children with acute lymphoblastic leukemia
N Hijiya, IM Van Der Sluis - Leukemia & lymphoma, 2016 - Taylor & Francis
Asparaginase is an integral component of multiagent chemotherapy regimens for the
treatment of children with acute lymphoblastic leukemia. Positive outcomes are seen in …
treatment of children with acute lymphoblastic leukemia. Positive outcomes are seen in …
Improved survival for children and young adults with T-lineage acute lymphoblastic leukemia: results from the Children's Oncology Group AALL0434 methotrexate …
SS Winter, KP Dunsmore, M Devidas… - Journal of Clinical …, 2018 - ascopubs.org
Purpose Early intensification with methotrexate (MTX) is a key component of acute
lymphoblastic leukemia (ALL) therapy. Two different approaches to MTX intensification exist …
lymphoblastic leukemia (ALL) therapy. Two different approaches to MTX intensification exist …
Impact of asparaginase discontinuation on outcome in childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group
S Gupta, C Wang, EA Raetz, R Schore… - Journal of clinical …, 2020 - ascopubs.org
PURPOSE Asparaginase (ASNase) is an important component of acute lymphoblastic
leukemia (ALL) treatment, but is often discontinued because of toxicity. Erwinia …
leukemia (ALL) treatment, but is often discontinued because of toxicity. Erwinia …
L‐asparaginase treatment in acute lymphoblastic leukemia A focus on Erwinia asparaginase
Asparaginases are a cornerstone of treatment protocols for acute lymphoblastic leukemia
(ALL) and are used for remission induction and intensification treatment in all pediatric …
(ALL) and are used for remission induction and intensification treatment in all pediatric …
Non-Hodgkin lymphoma in children and adolescents: progress through effective collaboration, current knowledge, and challenges ahead
V Minard-Colin, L Brugières, A Reiter… - Journal of Clinical …, 2015 - ascopubs.org
Non-Hodgkin lymphoma is the fourth most common malignancy in children, has an even
higher incidence in adolescents, and is primarily represented by only a few histologic …
higher incidence in adolescents, and is primarily represented by only a few histologic …
Acute lymphoblastic leukemia
CH Pui, WE Evans - New England Journal of Medicine, 1998 - Mass Medical Soc
Acute lymphoblastic leukemia (ALL) is diagnosed in 3000 to 4000 persons in the United
States each year; two thirds of them are children. 1, 2 The current rate of cure of nearly 80 …
States each year; two thirds of them are children. 1, 2 The current rate of cure of nearly 80 …
Should adolescents with acute lymphoblastic leukemia be treated as old children or young adults? Comparison of the French FRALLE-93 and LALA-94 trials
N Boissel, MF Auclerc, V Lhéritier, Y Perel… - Journal of Clinical …, 2003 - ascopubs.org
Purpose: To compare pediatric and adult therapeutic practices in the treatment of acute
lymphoblastic leukemia (ALL) in adolescents. Patients and Methods: From June 1993 to …
lymphoblastic leukemia (ALL) in adolescents. Patients and Methods: From June 1993 to …
Pharmacological and clinical evaluation of L-asparaginase in the treatment of leukemia
UK Narta, SS Kanwar, W Azmi - Critical reviews in oncology/hematology, 2007 - Elsevier
l-Asparaginase is an effective antineoplastic agent, used in the acute lymphoblastic
leukemia chemotherapy. It has been an integral part of combination chemotherapy protocols …
leukemia chemotherapy. It has been an integral part of combination chemotherapy protocols …
Comparison of Escherichia coli–asparaginase withErwinia-asparaginase in the treatment of childhood lymphoid malignancies: results of a randomized European …
M Duval, S Suciu, A Ferster, X Rialland… - Blood, The Journal …, 2002 - ashpublications.org
Asparaginase is an enzyme used in the treatment of acute lymphoblastic leukemia and
lymphoblastic lymphoma in children. It has minimal bone marrow toxicity. Its major side …
lymphoblastic lymphoma in children. It has minimal bone marrow toxicity. Its major side …