Nanoparticles for cancer therapy: a review of influencing factors and evaluation methods for biosafety
J Li, T Wu, S Li, X Chen, Z Deng, Y Huang - Clinical And Translational …, 2023 - Springer
Nanoparticles are widely used in the biomedical field for diagnostic and therapeutic
purposes due to their small size, high carrier capacity, and ease of modification, which …
purposes due to their small size, high carrier capacity, and ease of modification, which …
Surveilling cellular vital signs: toward label-free biosensors and real-time viability assays for bioprocessing
JN Rosenberg, NC Cady - Current Opinion in Biotechnology, 2021 - Elsevier
Highlights•Adapting cell viability assays from research to bioprocessing drives innovation.•
Multicellular compositions do not conform with standard staining or imaging …
Multicellular compositions do not conform with standard staining or imaging …
Meta-analysis of cellular toxicity for graphene via data-mining the literature and machine learning
Y Ma, J Wang, J Wu, C Tong, T Zhang - Science of The Total Environment, 2021 - Elsevier
Since graphene is currently incorporated into various consumer products and used in a
variety of applications, determining the relationships between the physicochemical …
variety of applications, determining the relationships between the physicochemical …
Exploring the Ocular Absorption Pathway of Fasudil Hydrochloride towards Developing a Nanoparticulate Formulation with Improved Performance
Rho-kinase (ROCK) inhibitors represent a new category of anti-glaucoma medications.
Among them, Fasudil hydrochloride, a selective ROCK inhibitor, has demonstrated …
Among them, Fasudil hydrochloride, a selective ROCK inhibitor, has demonstrated …
Oxidative Products of Curcumin Rather Than Curcumin Bind to Helicobacter Pylori Virulence Factor VacA and Are Required to Inhibit Its Vacuolation Activity
Curcumin is a hydrophobic polyphenol derived from turmeric with potent anti-oxidant, anti-
microbial, anti-inflammatory and anti-carcinogenic effects. Curcumin is degraded into …
microbial, anti-inflammatory and anti-carcinogenic effects. Curcumin is degraded into …
Actively targeted nanodelivery of echinomycin induces autophagy-mediated death in chemoresistant pancreatic cancer in vivo
A Thomas, A Samykutty, JG Gomez-Gutierrez, W Yin… - Cancers, 2020 - mdpi.com
Pancreatic cancer remains a recalcitrant neoplasm associated with chemoresistance and
high fatality. Because it is frequently resistant to apoptosis, exploiting autophagic cell death …
high fatality. Because it is frequently resistant to apoptosis, exploiting autophagic cell death …
Quantum Chemical and Biological Insights into Redox Activity of Metallacarborane Complexes in Cancer Cells
K Bednarska-Szczepaniak, K Hałagan… - Journal of Chemical …, 2024 - ACS Publications
A relationship between the electronic properties of metal ions in metallacarboranes and their
ability to modulate mitochondrial oxidase activity and membrane hyperpolarization in cancer …
ability to modulate mitochondrial oxidase activity and membrane hyperpolarization in cancer …
Simultaneous detection of multiple tumor-targeted gold nanoparticles in HER2-positive breast tumors using optoacoustic imaging
A Samykutty, KN Thomas, M McNally… - Radiology: Imaging …, 2023 - pubs.rsna.org
Purpose To develop optoacoustic, spectrally distinct, actively targeted gold nanoparticle–
based near-infrared probes (trastuzumab [TRA], TRA-Aurelia-1, and TRA-Aurelia-2) that can …
based near-infrared probes (trastuzumab [TRA], TRA-Aurelia-1, and TRA-Aurelia-2) that can …
[PDF][PDF] Review on the In Vitro Cytotoxicity Assessment in Accordance to the International Organization for Standardization (ISO).
MAM Shafiee, MAM Asri, SSS Alwi - Malaysian Journal of …, 2021 - researchgate.net
Cytotoxicity is a predominant biological evaluation applied to search for a suitable and non-
toxic bioactive compound and to determine the biocompatibility of medical devices-related …
toxic bioactive compound and to determine the biocompatibility of medical devices-related …
Newly synthesized derivatives with a thiosemicarbazide group reduce the viability of cancer cell lines. Acute toxicity assessment in Zebrafish (Danio rerio) early life …
ŁJ Walczak-Nowicka, A Szopa, M Pitucha, A Serefko… - Toxicology in Vitro, 2024 - Elsevier
Due to the variability and ability of tumor to mutate, as well as the heterogeneity of tumor
tissue, such drugs are sought that would act selectively and multidirectionally on the cancer …
tissue, such drugs are sought that would act selectively and multidirectionally on the cancer …