NDM metallo-β-lactamases and their bacterial producers in health care settings

W Wu, Y Feng, G Tang, F Qiao… - Clinical microbiology …, 2019 - Am Soc Microbiol
New Delhi metallo-β-lactamase (NDM) is a metallo-β-lactamase able to hydrolyze almost all
β-lactams. Twenty-four NDM variants have been identified in> 60 species of 11 bacterial …

The global ascendency of OXA-48-type carbapenemases

JDD Pitout, G Peirano, MM Kock… - Clinical microbiology …, 2019 - Am Soc Microbiol
Surveillance studies have shown that OXA-48-like carbapenemases are the most common
carbapenemases in Enterobacterales in certain regions of the world and are being …

Genetic diversity, biochemical properties, and detection methods of minor carbapenemases in Enterobacterales

RA Bonnin, AB Jousset, C Emeraud, S Oueslati… - Frontiers in …, 2021 - frontiersin.org
Gram-negative bacteria, especially Enterobacterales, have emerged as major players in
antimicrobial resistance worldwide. Resistance may affect all major classes of anti-gram …

Phenotypic and genotypic detection methods for antimicrobial resistance in ESKAPE pathogens

MM Muntean, AA Muntean… - Experimental and …, 2022 - spandidos-publications.com
Antimicrobial resistance (AMR) represents a growing public health problem worldwide.
Infections with such bacteria lead to longer hospitalization times, higher healthcare costs …

The revolution of lateral flow assay in the field of AMR detection

H Boutal, C Moguet, L Pommiès, S Simon, T Naas… - Diagnostics, 2022 - mdpi.com
The global spread of antimicrobial resistant (AMR) bacteria represents a considerable public
health concern, yet their detection and identification of their resistance mechanisms remain …

To be or not to be an OXA-48 carbapenemase

L Dabos, S Oueslati, S Bernabeu, RA Bonnin, L Dortet… - Microorganisms, 2022 - mdpi.com
Since the first description of OXA-48, more than forty variants have been recovered from
Enterobacterales isolates. Whereas some OXA-48-related enzymes have been reported as …

[HTML][HTML] Accuracy and applicability of different phenotypic methods for carbapenemase detection in Enterobacteriaceae: A systematic review and meta-analysis

H Zhong, ML Wu, WJ Feng, SF Huang… - Journal of global …, 2020 - Elsevier
Abstract Objectives Carbapenem-resistant Enterobacteriaceae (CRE) are a major public-
health threat. The most important mechanism of carbapenem resistance in CRE is …

False-positive carbapenem-hydrolyzing confirmatory tests due to ACT-28, a chromosomally encoded AmpC with weak carbapenemase activity from Enterobacter …

AB Jousset, S Oueslati, S Bernabeu… - Antimicrobial Agents …, 2019 - Am Soc Microbiol
In Enterobacter cloacae complex (ECC), the overproduction of the chromosome-encoded
cephalosporinase (cAmpC) associated with decreased outer membrane permeability may …

[HTML][HTML] Molecular, Genetic, and Biochemical Characterization of OXA-484 Carbapenemase, a Difficult-to-Detect R214G Variant of OXA-181

C Gonzalez, S Oueslati, M Rima, R Nermont, L Dortet… - Microorganisms, 2024 - mdpi.com
OXA-244, an R214G variant of OXA-48, is silently spreading worldwide likely because of
difficulties in detection using classical screening media. Here, we characterized two clinical …

Rapid detection of CTX-M-type ESBLs and carbapenemases directly from biological samples using the BL-DetecTool

H Volland, C Ballesté-Delpierre, D Szabó… - Journal of …, 2022 - academic.oup.com
Background Lateral flow immunoassays (LFIA) have shown their usefulness for detecting
CTX-M-and carbapenemase-producing Enterobacterales (CPEs) in bacterial cultures. Here …