Unmet needs in valvular heart disease

D Messika-Zeitoun, H Baumgartner… - European heart …, 2023 - academic.oup.com
Valvular heart disease (VHD) is the next epidemic in the cardiovascular field, affecting
millions of people worldwide and having a major impact on health care systems. With aging …

Great debate: all patients with asymptomatic severe aortic stenosis need valve replacement

B Iung, L Pierard, J Magne… - European Heart …, 2023 - academic.oup.com
Department of Cardiology III—Adult Congenital and Valvular Heart Disease, University
Hospital Muenster, Muenster, Germany Aortic stenosis (AS) has become a significant health …

Severe aortic stenosis detection by deep learning applied to echocardiography

G Holste, EK Oikonomou, BJ Mortazavi… - European Heart …, 2023 - academic.oup.com
Abstract Background and Aims Early diagnosis of aortic stenosis (AS) is critical to prevent
morbidity and mortality but requires skilled examination with Doppler imaging. This study …

[HTML][HTML] What matters most to patients with severe aortic stenosis when choosing treatment? Framing the conversation for shared decision making

NF Col, D Otero, BR Lindman, A Horne, MM Levack… - PloS one, 2022 - journals.plos.org
Background Guidelines recommend including the patient's values and preferences when
choosing treatment for severe aortic stenosis (sAS). However, little is known about what …

A Multimodal Video-Based AI Biomarker for Aortic Stenosis Development and Progression

EK Oikonomou, G Holste, N Yuan, A Coppi… - JAMA …, 2024 - jamanetwork.com
Importance Aortic stenosis (AS) is a major public health challenge with a growing
therapeutic landscape, but current biomarkers do not inform personalized screening and …

Self-supervised learning of echocardiogram videos enables data-efficient clinical diagnosis

G Holste, EK Oikonomou, B Mortazavi, Z Wang… - arXiv preprint arXiv …, 2022 - arxiv.org
Given the difficulty of obtaining high-quality labels for medical image recognition tasks, there
is a need for deep learning techniques that can be adequately fine-tuned on small labeled …

[HTML][HTML] The role of the N-terminal of the prohormone brain natriuretic peptide in predicting postoperative multiple organ dysfunction syndrome

P Duchnowski - Journal of Clinical Medicine, 2022 - mdpi.com
Background: Multiple organ dysfunction syndrome (MODS) is the progressive and
potentially reversible dysfunction of at least two organ systems in the course of an acute and …

[HTML][HTML] Impact of severe aortic stenosis on quality of life

JM Gracia Baena, JR Marsal Mora… - PLoS …, 2023 - journals.plos.org
Introduction Among individuals≥ 65 years old, aortic stenosis is highly prevalent and the
number of cases is expected to increase in the coming decades, due to the increased life …

[HTML][HTML] N-Terminal of the prohormone brain natriuretic peptide predicts postoperative cardiogenic shock requiring extracorporeal membrane oxygenation

P Duchnowski - Journal of Clinical Medicine, 2022 - mdpi.com
Aims: Heart valve surgery is associated with a risk of serious postoperative complications
including postoperative cardiogenic shock (described as postcardiotomy shock (PCS)). The …

Patterns of aortic valve replacement in Europe: adoption by age

T Rudolph, C Appleby, V Delgado, H Eltchaninoff… - Cardiology, 2023 - karger.com
Introduction: The management of patients with severe aortic stenosis may differ according to
patients' age. The aim of this analysis was to describe patterns of aortic valve replacement …