Biomarkers in acute kidney injury–pathophysiological basis and clinical performance

EV Schrezenmeier, J Barasch, K Budde… - Acta …, 2017 - Wiley Online Library
Various biomarkers of acute kidney injury (AKI) have been discovered and characterized in
the recent past. These molecules can be detected in urine or blood and signify structural …

Biomarkers of acute kidney injury: the pathway from discovery to clinical adoption

K Kashani, W Cheungpasitporn… - Clinical Chemistry and …, 2017 - degruyter.com
Acute kidney injury (AKI) is a common complication of critical illnesses and has a significant
impact on outcomes, including mortality and morbidities. Unfortunately, apart from …

Recommendations on acute kidney injury biomarkers from the acute disease quality initiative consensus conference: a consensus statement

M Ostermann, A Zarbock, S Goldstein… - JAMA network …, 2020 - jamanetwork.com
Importance In the last decade, new biomarkers for acute kidney injury (AKI) have been
identified and studied in clinical trials. Guidance is needed regarding how best to …

Neutrophil gelatinase-associated lipocalin measured on clinical laboratory platforms for the prediction of acute kidney injury and the associated need for dialysis …

C Albert, A Zapf, M Haase, C Röver… - American Journal of …, 2020 - Elsevier
Rationale & Objective The usefulness of measures of neutrophil gelatinase-associated
lipocalin (NGAL) in urine or plasma obtained on clinical laboratory platforms for predicting …

Acute kidney injury overview: from basic findings to new prevention and therapy strategies

SR Gonsalez, AL Cortês, RC da Silva, J Lowe… - Pharmacology & …, 2019 - Elsevier
Acute kidney injury (AKI) is defined as a decrease in kidney function within hours, which
encompasses both injury and impairment of renal function. AKI is not considered a …

The role of biomarkers in acute kidney injury

N Srisawat, JA Kellum - Critical care clinics, 2020 - criticalcare.theclinics.com
In the past 50 years, the diagnosis of acute kidney injury (AKI) has been mainly based on
serum creatinine. 1 It is well known that an increase in serum creatinine level occurs after a …

Advances in the study of subclinical AKI biomarkers

C Zou, C Wang, L Lu - Frontiers in Physiology, 2022 - frontiersin.org
Acute kidney injury (AKI) is a prevalent and serious illness in all clinical departments, with a
high morbidity and death rate, particularly in intensive care units, where prevention and …

Effects of cardiopulmonary bypass on renal perfusion, filtration, and oxygenation in patients undergoing cardiac surgery

L Lannemyr, G Bragadottir, V Krumbholz… - …, 2017 - pubs.asahq.org
Background Acute kidney injury is a common complication after cardiac surgery with
cardiopulmonary bypass. The authors evaluated the effects of normothermic …

Biomarkers for the early detection and prognosis of acute kidney injury

R Malhotra, ED Siew - Clinical journal of the American society of …, 2017 - journals.lww.com
AKI is an increasingly common disorder that is strongly linked to short-and long-term
morbidity and mortality. Despite a growing heterogeneity in its causes, providing a timely …

Biomarkers in acute kidney injury (AKI)

SH Teo, ZH Endre - Best practice & research Clinical anaesthesiology, 2017 - Elsevier
Acute kidney injury is common in critically ill patients and portends a significant impact on
mortality, progressive chronic kidney disease, and cardiovascular disease and mortality …