Bioconjugates of photon-upconversion nanoparticles for cancer biomarker detection and imaging

A Hlaváček, Z Farka, MJ Mickert, U Kostiv… - Nature …, 2022 - nature.com
The detection of cancer biomarkers in histological samples and blood is of paramount
importance for clinical diagnosis. Current methods are limited in terms of sensitivity …

Nanoparticle‐based bioaffinity assays: from the research laboratory to the market

Z Farka, JC Brandmeier, MJ Mickert… - Advanced …, 2024 - Wiley Online Library
Advances in the development of new biorecognition elements, nanoparticle‐based labels as
well as instrumentation have inspired the design of new bioaffinity assays. This review …

Assessing the reproducibility and up-scaling of the synthesis of Er,Yb-doped NaYF4-based upconverting nanoparticles and control of size, morphology, and optical …

E Andresen, F Islam, C Prinz, P Gehrmann, K Licha… - Scientific Reports, 2023 - nature.com
Lanthanide-based, spectrally shifting, and multi-color luminescent upconverting
nanoparticles (UCNPs) have received much attention in the last decades because of their …

Digital and analog detection of SARS-CoV-2 nucleocapsid protein via an upconversion-linked immunosorbent assay

JC Brandmeier, N Jurga, T Grzyb, A Hlavacek… - Analytical …, 2023 - ACS Publications
The COVID-19 crisis requires fast and highly sensitive tests for the early stage detection of
the SARS-CoV-2 virus. For detecting the nucleocapsid protein (N protein), the most …

Single-nanoparticle differential immunoassay for multiplexed gastric cancer biomarker monitoring

Z Huang, X Zhao, J Hu, C Zhang, X Xie, R Liu… - Analytical …, 2022 - ACS Publications
Precision medicine demands the best application of multiple unambiguous biomarkers to
bring uniform decisions in disease prognosis. The remarkable development of …

Ultrasensitive upconversion nanoparticle immunoassay for human serum cardiac troponin I detection achieved with resonant waveguide grating

YT Tseng, YC Chiu, VD Pham, WH Wu, TT Le-Vu… - ACS …, 2024 - ACS Publications
Selective detection of biomarkers at low concentrations in blood is crucial for the clinical
diagnosis of many diseases but remains challenging. In this work, we aimed to develop an …

Point-of-care detection of Monkeypox virus clades using high-performance upconversion nanoparticle-based lateral flow assay

B Jin, C Ma, C Zhang, H Yin, G Zhao, J Hu, Z Li - Microchimica Acta, 2024 - Springer
There is an urgent need for a point-of-care testing (POCT) method in developing and
underserved regions to distinguish between two Monkeypox virus (MPXV) clades, given …

Comparison of single and double pulse laser-induced breakdown spectroscopy for the detection of biomolecules tagged with photon-upconversion nanoparticles

Z Farka, K Vytisková, E Makhneva, E Zikmundová… - Analytica Chimica …, 2024 - Elsevier
Background Laser-induced breakdown spectroscopy (LIBS) is a well-recognized analytical
technique used for elemental analysis. This method is gaining considerable attention also in …

Chemiluminescence biosensor for the determination of cardiac troponin I (cTnI)

R Tannenberg, M Paul, B Röder, SL Gande… - Biosensors, 2023 - mdpi.com
Cardiac vascular diseases, especially acute myocardial infarction (AMI), are one of the
leading causes of death worldwide. Therefore cardio-specific biomarkers such as cardiac …

What digital immunoassays can learn from ambient analyte theory: A perspective

HH Gorris, T Soukka - Analytical Chemistry, 2022 - ACS Publications
Immunoassays are important tools for clinical diagnosis as well as environmental and food
analysis because they enable highly sensitive and quantitative measurements of analyte …