The importance of the Basidiomycete Cryptococcus neoformans to human health has
stimulated its development as an experimental model for both basic physiology and …

Cryptococcus neoformans is a fungal pathogen with worldwide distribution. Serological
studies of human populations show a high prevalence of human infection, which rarely …

The outcome of cryptococcal pneumonia correlates with local macrophage polarization
status, as M1 and M2 polarization marks protective and nonprotective responses …

Cryptococcosis, caused by Cryptococcus neoformans, has been demonstrated to be
controlled by T helper (Th) 1 cells while Th2 cells are associated with fungal growth and …

Background. Correlates of immune protection in patients with human immunodeficiency
virus (HIV)–associated cryptococcal meningitis are poorly defined. A clearer understanding …

Cryptococcus neoformans is a fungal pathogen that causes almost half a million deaths
each year. It is believed that most humans are infected with C. neoformans, possibly in a …

Copper homeostasis is important for virulence of the fungus Cryptococcus neoformans,
which can cause lethal meningoencephalitis in humans. Cryptococcus cells encounter high …

Cryptococcus neoformans, an opportunistic yeast pathogen, relies on a complex network of
stress response pathways that allow for proliferation in the host. In Saccharomyces …

Numerous virulence factors expressed by Cryptococcus neoformans modulate host
defenses by promoting nonprotective Th2-biased adaptive immune responses. Prior studies …

Cryptococcus neoformans is a leading cause of fungal brain infection, but the mechanism of
dissemination and dynamics of cerebral infection following pulmonary disease are poorly …