CDC25 phosphatases in cancer cells: key players? Good targets?
R Boutros, V Lobjois, B Ducommun - Nature Reviews Cancer, 2007 - nature.com
Abstract Cell division cycle 25 (CDC25) phosphatases regulate key transitions between cell
cycle phases during normal cell division, and in the event of DNA damage they are key …
cycle phases during normal cell division, and in the event of DNA damage they are key …
The Fos family of transcription factors and their role in tumourigenesis
K Milde-Langosch - European journal of cancer, 2005 - Elsevier
Members of the Fos family (c-Fos, FosB and its smaller splice variants, Fra-1 and Fra-2)
dimerise with Jun proteins to form the AP-1 transcription factor complex. Based on the …
dimerise with Jun proteins to form the AP-1 transcription factor complex. Based on the …
[HTML][HTML] The ovarian cancer oncobiome
Humans and other mammals are colonized by microbial agents across the kingdom which
can represent a unique microbiome pattern. Dysbiosis of the microbiome has been …
can represent a unique microbiome pattern. Dysbiosis of the microbiome has been …
[HTML][HTML] Role of the transcription factor FOSL1 in organ development and tumorigenesis
VV Sobolev, AZ Khashukoeva, OE Evina… - International journal of …, 2022 - mdpi.com
The transcription factor FOSL1 plays an important role in cell differentiation and
tumorigenesis. Primarily, FOSL1 is crucial for the differentiation of several cell lineages …
tumorigenesis. Primarily, FOSL1 is crucial for the differentiation of several cell lineages …
[PDF][PDF] Cdc25 phosphatases and cancer
K Kristjansdottir, J Rudolph - Chemistry & biology, 2004 - cell.com
The Cdc25 phosphatases function as key regulators of the cell cycle during normal
eukaryotic cell division and as mediators of the checkpoint response in cells with DNA …
eukaryotic cell division and as mediators of the checkpoint response in cells with DNA …
[HTML][HTML] Id proteins in cell growth and tumorigenesis
HA Sikder, MK Devlin, S Dunlap, B Ryu, RM Alani - Cancer cell, 2003 - cell.com
Since the gene encoding Id1 was cloned in 1990, Id proteins have been implicated in
regulating a variety of cellular processes, including cellular growth, senescence …
regulating a variety of cellular processes, including cellular growth, senescence …
Overexpression of long noncoding RNA PCAT-1 is a novel biomarker of poor prognosis in patients with colorectal cancer
X Ge, Y Chen, X Liao, D Liu, F Li, H Ruan, W Jia - Medical oncology, 2013 - Springer
Long noncoding RNAs (lncRNA) are emerging as key molecules in human cancer. Prostate
cancer–associated ncRNA transcripts 1 (PCAT-1), a lncRNA, has been recently revealed …
cancer–associated ncRNA transcripts 1 (PCAT-1), a lncRNA, has been recently revealed …
Overexpression of long noncoding RNA HOTAIR predicts a poor prognosis in patients with cervical cancer
L Huang, LM Liao, AW Liu, JB Wu, XL Cheng… - Archives of gynecology …, 2014 - Springer
Purpose The long noncoding RNA HOTAIR has been reported to be a good biomarker for
poor prognosis in a variety of human cancers. However, whether HOTAIR could serve as …
poor prognosis in a variety of human cancers. However, whether HOTAIR could serve as …
Constitutive activation of transcription factor AP‐1 in cervical cancer and suppression of human papillomavirus (HPV) transcription and AP‐1 activity in HeLa cells by …
The transcription factor AP‐1 plays a central role in the transcriptional regulation of specific
types of high‐risk human papillomaviruses (HPVs) such as HPV16 and HPV18, which are …
types of high‐risk human papillomaviruses (HPVs) such as HPV16 and HPV18, which are …
Global gene expression profiling and validation in esophageal squamous cell carcinoma and its association with clinical phenotypes
Purpose: Esophageal squamous cell carcinoma (ESCC) is an aggressive tumor with poor
prognosis. Understanding molecular changes in ESCC will enable identification of …
prognosis. Understanding molecular changes in ESCC will enable identification of …