The hippocampus provided the gateway into much of what we have learned about stress
and brain structural and functional plasticity, and this initial focus has expanded to other …

For the last five decades, science has managed to delineate the mechanisms by which
stress hormones can impact on the human brain. Receptors for glucocorticoids are found in …

The prefrontal cortex (PFC) is involved in working memory and self-regulatory and goal-
directed behaviors and displays remarkable structural and functional plasticity over the life …

Stress is a state of the mind, involving both brain and body as well as their interactions; it
differs among individuals and reflects not only major life events but also the conflicts and …

The WHO definition of health as complete wellbeing is no longer fit for purpose given the
rise of chronic disease. Machteld Huber and colleagues propose changing the emphasis …

The brain is the central organ for adaptation to experiences, including stressors, which are
capable of changing brain architecture as well as altering systemic function through …

Experiential factors shape the neural circuits underlying social and emotional behavior from
the prenatal period to the end of life. These factors include both incidental influences, such …

As the central organ of stress and adaptation to stressors, the brain plays a pivotal role in
behavioral and physiological responses that may lead to successful adaptation or to …

The brain is the key organ of stress reactivity, coping, and recovery processes. Within the
brain, a distributed neural circuitry determines what is threatening and thus stressful to the …

This review integrates Fredrickson's broaden-and-build theory of positive emotions with
advances in affective neuroscience regarding plasticity in the neural circuitry of emotions to …