Objective To elucidate the scientific advances made in the last 12 months within the realm of
osteoarthritis genetics, genomics, and epigenetics. This review paper highlights major …

Chronic pain is a prevalent condition with a multifaceted pathogenesis, where epigenetic
modifications, particularly DNA methylation, might play an important role. This review delves …

Our study aimed to identify differentially methylated regions (ie, genomic region where
multiple adjacent CpG sites show differential methylation) and their enriched genomic …

Nociceptive pain involves the activation of nociceptors without damage to the nervous
system, whereas neuropathic pain is related to an alteration in the central or peripheral …

Chronic musculoskeletal pain is often associated with lower socioeconomic status (SES).
SES correlates with psychological and environmental conditions that could contribute to the …

Abstract Compared to Non-Hispanic Whites (NHWs), individuals who self-identify as Non-
Hispanic Blacks (NHBs) in the United States experience more severe and disabling chronic …

Aberrant neuronal excitability in the anterior cingulate cortex (ACC) is implicated in cognitive
and affective pain processing. Such excitability may be amplified by activated circulating …

Introduction: Recent evidence suggests that vitamin D may interact with the epigenome and
play a role in the pain experience. In order for proper functioning to occur, there must be an …

Temporomandibular disorders (TMDs), collectively representing one of the most common
chronic pain conditions, have a substantial genetic component, but genetic variation alone …

Chronic pain is one of the major health problems in the world. Studies have shown that
chronic pain is closely related to epigenetics. Chronic pain can increased the level of DNA …