Cryptococcus: from environmental saprophyte to global pathogen
Cryptococcosis is a globally distributed invasive fungal infection that is caused by species
within the genus Cryptococcus which presents substantial therapeutic challenges. Although …
within the genus Cryptococcus which presents substantial therapeutic challenges. Although …
A holistic review on Cryptococcus neoformans
SS Rathore, J Sathiyamoorthy, C Lalitha… - Microbial …, 2022 - Elsevier
Cryptococcus neoformans is an encapsulated fungal pathogen that causes infection in
immunocompromised individuals such as HIV patients, organ transplant patients …
immunocompromised individuals such as HIV patients, organ transplant patients …
Fungal strategies to evade the host immune recognition
MJ Hernández-Chávez, LA Pérez-García… - Journal of Fungi, 2017 - mdpi.com
The recognition of fungal cells by the host immune system is key during the establishment of
a protective anti-fungal response. Even though the immune system has evolved a vast …
a protective anti-fungal response. Even though the immune system has evolved a vast …
Cryptococcus neoformans urease affects the outcome of intracellular pathogenesis by modulating phagolysosomal pH
MS Fu, C Coelho, CM De Leon-Rodriguez… - PLoS …, 2018 - journals.plos.org
Cryptococcus neoformans is a facultative intracellular pathogen and its interaction with
macrophages is a key event determining the outcome of infection. Urease is a major …
macrophages is a key event determining the outcome of infection. Urease is a major …
Cryptococcal pathogenic mechanisms: a dangerous trip from the environment to the brain
Cryptococcus neoformans is an opportunistic pathogenic yeast that causes serious
infections, most commonly of the central nervous system (CNS). C. neoformans is mainly …
infections, most commonly of the central nervous system (CNS). C. neoformans is mainly …
Streptococcus agalactiae cadD alleviates metal stress and promotes intracellular survival in macrophages and ascending infection during pregnancy
ML Korir, RS Doster, J Lu, MA Guevara… - Nature …, 2022 - nature.com
Perinatal infection with Streptococcus agalactiae, or Group B Streptococcus (GBS), is
associated with preterm birth, neonatal sepsis, and stillbirth. Here, we study the interactions …
associated with preterm birth, neonatal sepsis, and stillbirth. Here, we study the interactions …
Cryptococcus and Phagocytes: Complex Interactions that Influence Disease Outcome
Cryptococcus neoformans and C. gattii are fungal pathogens that cause life-threatening
disease. These fungi commonly enter their host via inhalation into the lungs where they …
disease. These fungi commonly enter their host via inhalation into the lungs where they …
Mechanisms of Cryptococcus neoformans-Mediated Host Damage
Cryptococcus neoformans is not usually considered a cytotoxic fungal pathogen but there is
considerable evidence that this microbe can damage host cells and tissues. In this essay …
considerable evidence that this microbe can damage host cells and tissues. In this essay …
Fungal mechanisms of intracellular survival: what can we learn from bacterial pathogens?
PV Stuckey, FH Santiago-Tirado - Infection and Immunity, 2023 - Am Soc Microbiol
Fungal infections represent a major, albeit neglected, public health threat with serious
medical and economic burdens globally. With unacceptably high mortality rates, invasive …
medical and economic burdens globally. With unacceptably high mortality rates, invasive …
Internalized Cryptococcus neoformans activates the canonical caspase-1 and the noncanonical caspase-8 inflammasomes
Cryptococcus neoformans is an opportunistic fungal pathogen that causes cryptococccosis
in immunocompromised patients as well as immunocompetent individuals. Host cell surface …
in immunocompromised patients as well as immunocompetent individuals. Host cell surface …