Molecular probes, chemosensors, and nanosensors for optical detection of biorelevant molecules and ions in aqueous media and biofluids

J Krämer, R Kang, LM Grimm, L De Cola… - Chemical …, 2022 - ACS Publications
Synthetic molecular probes, chemosensors, and nanosensors used in combination with
innovative assay protocols hold great potential for the development of robust, low-cost, and …

Recent advancements of nanomedicine in neurodegenerative disorders theranostics

S Mukherjee, VS Madamsetty… - Advanced Functional …, 2020 - Wiley Online Library
Recent times have witnessed an upsurge in the incidence of neurodegenerative disorders
such as Alzheimer's disease, Parkinson's disease, Huntington's disease, Prion disease, and …

Cross-frequency coupling between gamma oscillations and deep brain stimulation frequency in Parkinson's disease

M Muthuraman, M Bange, N Koirala, D Ciolac, B Pintea… - Brain, 2020 - academic.oup.com
The disruption of pathologically enhanced beta oscillations is considered one of the key
mechanisms mediating the clinical effects of deep brain stimulation on motor symptoms in …

Neuroprotective and symptomatic effects of cannabidiol in an animal model of Parkinson's disease

C Giuliano, M Francavilla, G Ongari, A Petese… - International Journal of …, 2021 - mdpi.com
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of
dopaminergic neurons in the Substantia Nigra pars compacta, leading to classical PD motor …

[HTML][HTML] Local field potential activity dynamics in response to deep brain stimulation of the subthalamic nucleus in Parkinson's disease

C Wiest, G Tinkhauser, A Pogosyan, M Bange… - Neurobiology of …, 2020 - Elsevier
Local field potentials (LFPs) may afford insight into the mechanisms of action of deep brain
stimulation (DBS) and potential feedback signals for adaptive DBS. In Parkinson's disease …

Internal ribosome entry site (IRES)-mediated translation and its potential for novel mRNA-based therapy development

R Marques, R Lacerda, L Romão - Biomedicines, 2022 - mdpi.com
Many conditions can benefit from RNA-based therapies, namely, those targeting internal
ribosome entry sites (IRESs) and their regulatory proteins, the IRES trans-acting factors …

Nanoparticle-based technology approaches to the management of neurological disorders

TM Sim, D Tarini, ST Dheen, BH Bay… - International Journal of …, 2020 - mdpi.com
Neurological disorders are the most devastating and challenging diseases associated with
the central nervous system (CNS). The blood-brain barrier (BBB) maintains homeostasis of …

Small Scale, Big Impact: Nanotechnology-Enhanced Drug Delivery for Brain Diseases

K Miao, X Xia, Y Zou, B Shi - Molecular Pharmaceutics, 2024 - ACS Publications
Central nervous system (CNS) diseases, ranging from brain cancers to neurodegenerative
disorders like dementia and acute conditions such as strokes, have been heavily burdening …

Lectins from the Edible Mushroom Agaricus bisporus and Their Therapeutic Potentials

W Tirta Ismaya, RR Tjandrawinata, H Rachmawati - Molecules, 2020 - mdpi.com
The mushroom Agaricus bisporus secretes biologically active compounds and proteins with
benefits for human health. Most reported proteins from A. bisporus are tyrosinases and …

[HTML][HTML] Beneficial nonmotor effects of subthalamic and pallidal neurostimulation in Parkinson's disease

HS Dafsari, MG dos Santos Ghilardi… - Brain stimulation, 2020 - Elsevier
Background Subthalamic (STN) and pallidal (GPi) deep brain stimulation (DBS) improve
quality of life, motor, and nonmotor symptoms (NMS) in advanced Parkinson's disease (PD) …