Sociocultural changes in the human–animal relationship have led to increasing demands for
animal welfare in biomedical research. The 3R concept is the basis for bringing this demand …

Mitochondria share extensive evolutionary conservation across nearly all living species.
This homology allows robust insights to be gained into pathophysiologic mechanisms and …

Sporothrix brasiliensis has emerged as the most virulent species in the Sporothrix schenckii
complex, accounting for sporotrichosis. Albeit the new insights into the understanding of host …

Previous work pointed to a critical role of excessive production of reactive oxygen species
(ROS) in increased radiation hematopoietic death in GFP mice. Meanwhile, enhanced …

Skeletal muscle activation using optogenetics has emerged as a promising technique for
inducing noninvasive muscle contraction and assessing muscle function both in vivo and in …

Simple Summary Gene editing technology is expected to be an effective way to establish
animal models of human diseases. Using spermatogonial stem cells and sperm as gene …

To improve the efficiency of the production of transgenic cloned goats by somatic cell
nuclear transfer (SCNT), the development of reconstructed embryos of first‐generation (G1) …

Axonal growth and guidance at the ventral floor plate is here followed $\textit {in vivo} $ in
real time at high resolution by light-sheet microscopy along several hundred micrometers of …

The smallest natural antibody fragments currently available are single-domain antibodies
obtained from camelid species and sharks (variable new antigen receptors). These …

Algunas células endoteliales meníngeas (CEM) forman una monocapa en la parte interna
de los vasos sanguíneos que irrigan al cerebro. Por su proximidad a las células cerebrales …