A wide array of microorganisms, including many novel, phylogenetically deeply rooted taxa,
survive and thrive in extreme environments. These unique and reduced-complexity …

Despite the surge of microbial genome data, experimental testing is important to confirm
inferences about the cell biology, ecological roles and evolution of microorganisms. As the …

Compared to bacteria, our knowledge of archaeal biology is limited. Historically,
microbiologists have mostly relied on culturing and single-gene diversity surveys to …

Numerous diverse microorganisms reside in the cold desert soils of continental Antarctica,
though we lack a holistic understanding of the metabolic processes that sustain them. Here …

Candidate phyla radiation (CPR) bacteria and DPANN archaea are unisolated, small-celled
symbionts that are often detected in groundwater. The effects of groundwater geochemistry …

When it comes to the investigation of key ecosystems in the world, we often omit salt from the
ecological recipe. In fact, despite occupying almost half of the volume of inland waters and …

The organisms thriving under extreme conditions better than any other organism living on
Earth, fascinate by their hostile growing parameters, physiological features, and their …

CRISPR–Cas systems defend prokaryotic cells from invasive DNA of viruses, plasmids and
other mobile genetic elements. Here, we show using metagenomics, metatranscriptomics …

Throughout the golden age of antibiotic discovery, Streptomyces have been unsurpassed for
their ability to produce bioactive metabolites. Yet, this success has been hampered by …

The recently discovered DPANN archaea are a potentially deep-branching, monophyletic
radiation of organisms with small cells and genomes. However, the monophyly and early …