Human cytomegalovirus (HCMV) infection remains a major cause of morbidity in patient
populations. In certain clinical settings, it is the reactivation of the pre‐existing latent infection …

Herpes simplex virus type 1 (HSV-1; human herpesvirus 1) and varicella-zoster virus (VZV;
human herpesvirus 3) are human neurotropic alphaherpesviruses that cause lifelong …

Herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) have co-evolved with humans for
thousands of years and are present at a high prevalence in the population worldwide. HSV …

STING (stimulator of IFN genes) activates the IFN-dependent innate immune response to
infection on sensing the presence of DNA in cytosol. The quantity of STING accumulating in …

After infecting peripheral sites, herpes simplex virus (HSV) invades the nervous system and
initiates latent infection in sensory neurons. Establishment and maintenance of HSV latency …

Herpes simplex virus type 1 (HSV-1), a neurotropic herpes virus, is able to establish a
lifelong latent infection in the human host. Following primary replication in mucosal epithelial …

Herpes simplex virus type 1 (HSV-1) is capable of causing a latent infection in sensory
neurons that lasts for the lifetime of the host. The primary infection is resolved following the …

The issue of whether viruses are subject to restriction by endogenous microRNAs (miRNAs)
and/or by virus-induced small interfering RNAs (siRNAs) in infected human somatic cells …

It has previously been assumed that the generally high stability of microRNAs (miRNAs)
reflects their tight association with Argonaute (Ago) proteins, essential components of the …

MicroRNAs comprise a large family of short, non-coding RNAs that are present in most
eukaryotic organisms and are typically involved in downregulating the expression of protein …