Ion channels are integral membrane proteins present on the plasma membrane as well as
intracellular membranes. In the human genome, there are more than 400 known genes …

Cl− intracellular channels (CLICs) are a family of six evolutionary conserved cytosolic
proteins that exist in both soluble and membrane-associated forms; however, their functions …

Membrane protrusion and adhesion to the extracellular matrix, which involves the extension
of actin filaments and formation of adhesion complexes, are the fundamental processes for …

The ambiguous molecular mechanism remains a leading cause for the high mortality rate of
liver cancer. An evident iron overload has been unveiled in liver cancer cell proliferation …

Intracellular organelles are membranous structures central for maintaining cellular
physiology and the overall health of the cell. To maintain cellular function, intracellular …

Background: A membrane protein interaction with lipids shows distinct specificity in terms of
the sterol structure. The structure of the sterol's polar headgroup, steroidal rings, and …

New fluorescent polymeric sensors containing in situ photogenerated gold nanoparticles
(Au NPs) and fluorescein-based copolymers are reported. They are tested as efficient …

Abstract Chloride Intracellular Channel (CLIC) family members uniquely transition between
soluble and membrane-associated conformations. Despite decades of extensive functional …

The lack of in-depth knowledge about the molecular determinants of glioblastoma (GBM)
occurrence and progression, combined with few effective and BBB crossing-targeted …

This study aimed to explore the effects of CLIC 1 gene silencing on proliferation, migration,
invasion and apoptosis of human gallbladder cancer (GBC). GBC and normal gallbladder …