High‐aspect‐ratio nanostructured surfaces as biological metamaterials
SG Higgins, M Becce… - Advanced …, 2020 - Wiley Online Library
Materials patterned with high‐aspect‐ratio nanostructures have features on similar length
scales to cellular components. These surfaces are an extreme topography on the cellular …
scales to cellular components. These surfaces are an extreme topography on the cellular …
Topographic cues guiding cell polarization via distinct cellular mechanosensing pathways
W Liu, Q Sun, ZL Zheng, YT Gao, GY Zhu, Q Wei, JZ Xu… - Small, 2022 - Wiley Online Library
Cell polarization exists in a variety of tissues to regulate cell behaviors and functions. Space
constraint (spatially limiting cell extension) and adhesion induction (guiding adhesome …
constraint (spatially limiting cell extension) and adhesion induction (guiding adhesome …
Cellular and subcellular contact guidance on microfabricated substrates
C Leclech, C Villard - Frontiers in bioengineering and biotechnology, 2020 - frontiersin.org
Topography of the extracellular environment is now recognized as a major biophysical
regulator of cell behavior and function. The study of the influence of patterned substrates on …
regulator of cell behavior and function. The study of the influence of patterned substrates on …
Engineering cell alignment in vitro
Cell alignment plays a critical role in various cell behaviors including cytoskeleton
reorganization, membrane protein relocation, nucleus gene expression, and ECM …
reorganization, membrane protein relocation, nucleus gene expression, and ECM …
Physical non-viral gene delivery methods for tissue engineering
The integration of gene therapy into tissue engineering to control differentiation and direct
tissue formation is not a new concept; however, successful delivery of nucleic acids into …
tissue formation is not a new concept; however, successful delivery of nucleic acids into …
Designing electrospun fiber platforms for efficient delivery of genetic material and genome editing tools
Electrospun fibers are versatile biomaterial platforms with great potential to support
regeneration. Electrospun fiber characteristics such as fiber diameter, degree of alignment …
regeneration. Electrospun fiber characteristics such as fiber diameter, degree of alignment …
[HTML][HTML] Dynamic topographical control of mesenchymal stem cells by culture on responsive poly (ε-caprolactone) surfaces
There is clear, emerging evidence in the literature supporting the influence of surface
topography on various cell phenotypes.[1–5] Recent advancements in mechanobiology …
topography on various cell phenotypes.[1–5] Recent advancements in mechanobiology …
Nanotopographical modulation of cell function through nuclear deformation
K Wang, A Bruce, R Mezan, A Kadiyala… - … applied materials & …, 2016 - ACS Publications
Although nanotopography has been shown to be a potent modulator of cell behavior, it is
unclear how the nanotopographical cue, through focal adhesions, affects the nucleus …
unclear how the nanotopographical cue, through focal adhesions, affects the nucleus …
[PDF][PDF] Triboelectric nanogenerator accelerates highly efficient nonviral direct conversion and in vivo reprogramming of fibroblasts to functional neuronal cells
DOI: 10.1002/adma. 201601900 minimal safety issues, in clinical settings.[8d] A study
reported nonviral polymer nanoparticle-mediated direct conversion of mouse fibroblasts to …
reported nonviral polymer nanoparticle-mediated direct conversion of mouse fibroblasts to …
Hipster microcarriers: exploring geometrical and topographical cues of non-spherical microcarriers in biomedical applications
Structure and organisation are key aspects of the native tissue environment, which ultimately
condition cell fate via a myriad of processes, including the activation of …
condition cell fate via a myriad of processes, including the activation of …