Novel quinoline-based thiosemicarbazide derivatives: synthesis, DFT calculations, and investigation of antitubercular, antibacterial, and antifungal activities

E Özcan, SK Vagolu, MG Gündüz… - ACS …, 2023 - ACS Publications
The discovery of new antimicrobial agents as a means of treating drug-resistant microbial
pathogens is of utmost significance to overcome their immense risk to human well-being …

[HTML][HTML] Pd-, Cu-, and Ni-Catalyzed Reactions: A Comprehensive Review of the Efficient Approaches towards the Synthesis of Antibacterial Molecules

A Zia, S Khalid, N Rasool, N Mohsin, M Imran, SI Toma… - Pharmaceuticals, 2024 - mdpi.com
A strong synthetic tool for many naturally occurring chemicals, polymers, and
pharmaceutical substances is transition metal-catalyzed synthesis. A serious concern to …

Linking quinoline ring to 5-nitrofuran moiety via sulfonyl hydrazone bridge: Synthesis, structural characterization, DFT studies, and evaluation of antibacterial and …

ŞD Doğan, E Özcan, Y Çetinkaya, Mİ Han… - Journal of Molecular …, 2023 - Elsevier
In the present work, we report the synthesis, structural characterization, and computational
studies of (E)-N'-((5-nitrofuran-2-yl) methylene) quinoline-8-sulfonohydrazide (QNF) as a …

Benzothiazole derivatives as effective α-glucosidase inhibitors: an insight study of structure-activity relationships and molecular targets

Z Khalifa, R Upadhyay, AB Patel - Medicinal Chemistry Research, 2024 - Springer
In treating the major metabolic disorder diabetes mellitus type-2, the α-glucosidase enzyme
inhibitors play an effective role due to their vital capability of polysaccharide hydrolyzation. A …

AlCl3-Catalyzed Cascade Reactions of 1,2,3-Trimethoxybenzene and Adipoyl Chloride: Spectroscopic Investigations and Density Functional Theory Studies

Y Çetinkaya, T Artunç, A Menzek - ACS omega, 2022 - ACS Publications
The reaction of 1, 2, 3-trimethoxybenzene with adipoyl chloride in the presence of AlCl3
gave two isomeric cyclopentene derivatives, 1, 6-bis (2, 3, 4-trimethoxyphenyl) hexane-1, 6 …

[HTML][HTML] A tandem strategy for the synthesis of 2-aminobenzothiazoles via manganese catalyzed CS bond formation

T Aneeja, A Chandravarkar, G Anilkumar - Catalysis Communications, 2024 - Elsevier
The first manganese catalyzed tandem methodology for the synthesis of 2-
aminobenzothiazoles from 2-bromophenyl isothiocyanate and differently substituted amines …

Investigation of cholinesterase and α-glucosidase enzyme activities, and molecular docking and dft studies for 1, 2-disubstituted cyclopentane derivatives with phenyl …

T Artunç, Y Çetinkaya, P Taslimi, A Menzek - Molecular Diversity, 2024 - Springer
Abstract Six known products (4–9) were prepared from reaction of adipoyl chloride with 1, 2,
3-trimethoxybenzene according to the literature. From (2, 3, 4-trimethoxyphenyl)(2-(2, 3, 4 …

N-Iodosuccinimide mediated intramolecular oxidative C(sp2)-S bond formation for the synthesis of 2-aminobenzothiazole derivatives

AA Jichkar, IA Opai, NN Karade - Journal of Sulfur Chemistry, 2022 - Taylor & Francis
An extremely efficient synthetic method for the preparation of 2-aminobenzothiazole
derivatives starting from arylthioureas by using N-iodosuccinimide has been reported. This …

Copper catalyzed CN-bond formation and synthesis of Imidazopyridinone derivatives

ŞD Doğan, M Ongun - International Journal of Chemistry and …, 2022 - dergipark.org.tr
The formation of the C–N bond is critical because it allows for the incorporation of nitrogen
into organic molecules. Despite significant advances in this area, the formation of the C–N …