Cancer cells are characterized by a metabolic shift in cellular energy production,
orchestrated by the transcription factor HIF-1α, from mitochondrial oxidative phosphorylation …

The blood–brain barrier (BBB) is the interface between the central nervous system and
systemic circulation. It tightly regulates what enters and is removed from the brain …

Ultrahigh magnetic fields offer significantly higher signal-to-noise ratio, and several
magnetic resonance applications additionally benefit from a higher contrast-to-noise ratio …

Chemical exchange saturation transfer (CEST) imaging is a novel contrast mechanism,
relying on the exchange between mobile protons in amide (-NH), amine (-NH 2) and …

Purpose The aim of this study was to translate the T1ρ‐based dynamic glucose‐enhanced
(DGEρ) experiment from ultrahigh magnetic field strengths to a clinical field strength of 3 T …

The ability of CEST MRI to detect the presence of millimolar concentrations of non‐metallic
contrast agents has made it possible to study, non‐invasively, important biological …

Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) detects
molecules in their natural forms in a sensitive and non-invasive manner. This makes it a …

The accumulation of mutant huntingtin protein aggregates in neurons is a pathological
hallmark of Huntington's disease (HD). The glymphatic system, a brain-wide perivascular …

In this study, we applied on-resonance variable delay multiple pulse (onVDMP) MRI to study
D-glucose uptake in a mouse model of Alzheimer's disease (AD) tauopathy and …

Molecular imaging is becoming an indispensable tool to pursue precision medicine.
However, quickly translating newly developed magnetic resonance imaging (MRI) agents …