Applications of multi‐omics analysis in human diseases

C Chen, J Wang, D Pan, X Wang, Y Xu, J Yan… - MedComm, 2023 - Wiley Online Library
Multi‐omics usually refers to the crossover application of multiple high‐throughput screening
technologies represented by genomics, transcriptomics, single‐cell transcriptomics …

[HTML][HTML] Multi-omics approaches to disease

Y Hasin, M Seldin, A Lusis - Genome biology, 2017 - Springer
High-throughput technologies have revolutionized medical research. The advent of
genotyping arrays enabled large-scale genome-wide association studies and methods for …

[HTML][HTML] Engineering triangular carbon quantum dots with unprecedented narrow bandwidth emission for multicolored LEDs

F Yuan, T Yuan, L Sui, Z Wang, Z Xi, Y Li, X Li… - Nature …, 2018 - nature.com
Carbon quantum dots (CQDs) have emerged as promising materials for optoelectronic
applications on account of carbon's intrinsic merits of high stability, low cost, and …

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

A Gusev, N Mancuso, H Won, M Kousi, HK Finucane… - Nature …, 2018 - nature.com
Genome-wide association studies (GWAS) have identified over 100 risk loci for
schizophrenia, but the causal mechanisms remain largely unknown. We performed a …

Marine environmental epigenetics

JM Eirin-Lopez, HM Putnam - Annual review of marine science, 2019 - annualreviews.org
Marine organisms' persistence hinges on the capacity for acclimatization and adaptation to
the myriad of interacting environmental stressors associated with global climate change. In …

From profiles to function in epigenomics

SH Stricker, A Köferle, S Beck - Nature Reviews Genetics, 2017 - nature.com
Myriads of epigenomic features have been comprehensively profiled in health and disease
across cell types, tissues and individuals. Although current epigenomic approaches can …

Exploiting induced and natural epigenetic variation for crop improvement

NM Springer, RJ Schmitz - Nature reviews genetics, 2017 - nature.com
Plant breeding has traditionally relied on combining the genetic diversity present within a
species to develop combinations of alleles that provide desired traits. Epigenetic diversity …

Ecological plant epigenetics: Evidence from model and non‐model species, and the way forward

CL Richards, C Alonso, C Becker, O Bossdorf… - Ecology …, 2017 - Wiley Online Library
Growing evidence shows that epigenetic mechanisms contribute to complex traits, with
implications across many fields of biology. In plant ecology, recent studies have attempted to …

[HTML][HTML] Histone modifications and non-coding RNAs: mutual epigenetic regulation and role in pathogenesis

IV Bure, MV Nemtsova, EB Kuznetsova - International Journal of …, 2022 - mdpi.com
In the last few years, more and more scientists have suggested and confirmed that
epigenetic regulators are tightly connected and form a comprehensive network of regulatory …

Epigenetics in natural animal populations

J Hu, RDH Barrett - Journal of Evolutionary Biology, 2017 - academic.oup.com
Phenotypic plasticity is an important mechanism for populations to buffer themselves from
environmental change. While it has long been appreciated that natural populations possess …