While asthma is considered an inflammatory disorder of the conducting airways, it is
becoming increasingly apparent that the disease is heterogeneous with respect to …

Melasma is a commonly acquired hypermelanosis that affects sun-exposed areas of the
skin, with frequent facial involvement. Its histologic manifestations are evident in the …

The versatile role of mast cells in allergy, in innate immune responses and in the regulation
of tissue homeostasis is well recognized. However, it is often not made clear that most mast …

BACKGROUND: Severe anaphylaxis to honeybee or vespid stings is associated with a
variety of risk factors, which are poorly defined. OBJECTIVE: Our aim was to evaluate the …

Mast cells are rich in proteases, which are the major proteins of intracellular granules and
are released with histamine and heparin by activated cells. Most of these proteases are …

Mast cells (MCs) are traditionally thought of as a nuisance for its host, for example, by
causing many of the symptoms associated with allergic reactions. In addition, recent …

Mast cells are best known for their potent effector functions in allergic disorders. In recent
years, however, mast cells have been identified to be involved in a surprisingly complex …

Mast cells are tissue-resident immune cells that release immuno-modulators, chemo-
attractants, vasoactive compounds, neuropeptides and growth factors in response to …

The present approach to the diagnosis, management and follow‐up of anaphylaxis during
anaesthesia varies in the Scandinavian countries. The main purpose of these Scandinavian …

Observations of increased numbers of mast cells at sites of chronic inflammation have been
reported for over a hundred years. Light and electron microscopic evidence of mast cell …