Dysregulation of the immune system is associated with many pathologies, including
cardiovascular diseases, diabetes, and cancer. To date, the most commonly used models in …

A variety of in vivo experimental models have been established for the studies of human
cancer using both cancer cell lines and patient-derived xenografts (PDXs). In order to meet …

Redox biology is a very quickly developing area of modern biological sciences, and roles of
redox homeostasis in health and disease have recently received tremendous attention …

Newly hatched chickens are confronted by a wide array of pathogenic microbes because
their adaptive immune defences have limited capabilities to control these pathogens. In such …

The poultry industry has improved genetics, nutrition, and management practices, resulting
in fast-growing chickens; however, disturbances during embryonic development may affect …

The integrated innate immune features of the calcareous egg and its contents are a critical
underpinning of the remarkable evolutionary success of the Aves clade. Beginning at the …

The reduction of antimicrobial resistance is a major challenge for the scientific community. In
a few decades, infections by resistant bacteria are forecasted to be the main cause of death …

Methionine (Met) is an essential and first limiting amino acid in the poultry diet that plays a
significant role in chicken embryonic development and growth. The present study examined …

Genome sequencing of the teleost Atlantic cod demonstrated loss of the Major
Histocompatibility Complex (MHC) class II, an extreme gene expansion of MHC class I and …

Background Lipopolysaccharide (LPS) induces acute liver injury and the complex
mechanisms include the activation of toll like receptor 4 (TLR4) signaling pathway in many …