[HTML][HTML] Benzodiazepines in the management of seizures and status epilepticus: a review of routes of delivery, pharmacokinetics, efficacy, and tolerability
R Kienitz, L Kay, I Beuchat, S Gelhard… - CNS drugs, 2022 - Springer
Status epilepticus (SE) is an acute, life-threatening medical condition that requires
immediate, effective therapy. Therefore, the acute care of prolonged seizures and SE is a …
immediate, effective therapy. Therefore, the acute care of prolonged seizures and SE is a …
Guidelines for the evaluation and management of status epilepticus
Status epilepticus (SE) treatment strategies vary substantially from one institution to another
due to the lack of data to support one treatment over another. To provide guidance for the …
due to the lack of data to support one treatment over another. To provide guidance for the …
Evidence-based guideline: treatment of convulsive status epilepticus in children and adults: report of the Guideline Committee of the American Epilepsy Society
T Glauser, S Shinnar, D Gloss, B Alldredge… - Epilepsy …, 2016 - journals.sagepub.com
CONTEXT: The optimal pharmacologic treatment for early convulsive status epilepticus is
unclear. OBJECTIVE: To analyze efficacy, tolerability and safety data for anticonvulsant …
unclear. OBJECTIVE: To analyze efficacy, tolerability and safety data for anticonvulsant …
[HTML][HTML] Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial
Background Phenytoin is the recommended second-line intravenous anticonvulsant for
treatment of paediatric convulsive status epilepticus in the UK; however, some evidence …
treatment of paediatric convulsive status epilepticus in the UK; however, some evidence …
[HTML][HTML] A review of febrile seizures: recent advances in understanding of febrile seizure pathophysiology and commonly implicated viral triggers
Febrile seizures are one of the commonest presentations in young children, with a 2-5%
incidence in Western countries. Though they are generally benign, with rare long-term …
incidence in Western countries. Though they are generally benign, with rare long-term …
Drug treatment of epilepsy in adults
D Schmidt, SC Schachter - Bmj, 2014 - bmj.com
Epilepsy is a serious, potentially life shortening brain disorder, the symptoms of which can
be successfully treated in most patients with one or more antiepileptic drug. About two in …
be successfully treated in most patients with one or more antiepileptic drug. About two in …
Why won't it stop? The dynamics of benzodiazepine resistance in status epilepticus
Status epilepticus is a life-threatening neurological emergency that affects both adults and
children. Approximately 36% of episodes of status epilepticus do not respond to the current …
children. Approximately 36% of episodes of status epilepticus do not respond to the current …
Status epilepticus in adults
JP Betjemann, DH Lowenstein - The Lancet Neurology, 2015 - thelancet.com
Status epilepticus is a common neurological emergency with considerable associated
health-care costs, morbidity, and mortality. The definition of status epilepticus as a prolonged …
health-care costs, morbidity, and mortality. The definition of status epilepticus as a prolonged …
Benzodiazepines in epilepsy: pharmacology and pharmacokinetics
J Riss, J Cloyd, J Gates, S Collins - Acta neurologica …, 2008 - Wiley Online Library
Benzodiazepines (BZDs) remain important agents in the management of epilepsy. They are
drugs of first choice for status epilepticus and seizures associated with post‐anoxic insult …
drugs of first choice for status epilepticus and seizures associated with post‐anoxic insult …
[HTML][HTML] Pharmacotherapy for status epilepticus
Status epilepticus (SE) represents the most severe form of epilepsy. It is one of the most
common neurologic emergencies, with an incidence of up to 61 per 100,000 per year and …
common neurologic emergencies, with an incidence of up to 61 per 100,000 per year and …