Enhancer of zeste homolog 2 inhibitors (EZH2i) have garnered increased attention owing to
their anticancer activity by targeting EZH2, a well-known cancer-promoting factor. However …

There is a growing interest to understand the role and mechanism of action of microRNAs
(miRNAs) in cancer. The miRNAs are defined as short non-coding RNAs (18-22nt) that …

Motivation Deep neural network (DNN) algorithms were utilized in predicting various
biomedical phenotypes recently, and demonstrated very good prediction performances …

Long-term follow-up data indicates that 1/4 patients with acute kidney injury (AKI) will
develop to chronic kidney disease (CKD). Our previous studies have demonstrated that …

The number of patients with diabetic nephropathy (DN) is still on the rise worldwide, and this
requires the development of new therapeutic strategies. Recent reports have highlighted …

Pancreatic cancer (PC) is a malignant tumor that is difficult to diagnose and treat. Circular
RNAs (circRNAs) are biomarkers that may be used to diagnose certain cancers or act as …

Breast cancer is the most common cancer and leading cause of cancer death among
women worldwide, encompassing a wide heterogeneity of subtypes with different clinical …

Ethnopharmacological relevance Laminaria japonica, a brown seaweed, has been used in
Traditional Chinese Medicine (TCM) to treat a variety of diseases including lung cancer. Aim …

The cancer secretome comprises factors secreted by tumors, including cytokines, growth
factors, proteins from the extracellular matrix (ECM), proteases and protease inhibitors …

The Wnt/β-catenin signaling pathway is associated with the regulation of cancer stem cells,
and it can be driven by epigenetic modifications. Here, we aim to identify epigenetic …