Intrapulmonary arteriovenous anastomoses (IPAVA) have been known to exist in human
lungs for over 60 years. The majority of the work in this area has largely focused on …

Doherty, Connor J., Jou-Chung Chang, Benjamin P. Thompson, Erik R. Swenson, Glen E.
Foster, and Paolo B. Dominelli. The impact of acetazolamide and methazolamide on …

Key points The mechanism (s) that regulate hypoxia‐induced blood flow through
intrapulmonary arteriovenous anastomoses (QIPAVA) are currently unknown. Our previous …

Acetazolamide (AZ), a carbonic anhydrase inhibitor used for preventing altitude illness
attenuates hypoxic pulmonary vasoconstriction (HPV) while improving oxygenation …

Abstract Matthias Peter Hilty, Andrea Mueller, Daniela Flück, Christoph Siebenmann, Peter
Rasmussen, Stefanie Keiser, Katja Auinger, Carsten Lundby, and Marco Maggiorini. Effect …

Hypoxic pulmonary vasoconstriction (HPV) is a well-characterized vascular response to low
oxygen pressures and is involved in life-threatening conditions such as high-altitude …

It has been widely believed that human free divers were immune to decompression sickness
because the only inert gas added during a breath-hold dive is the nitrogen (N2) that remains …

Evidence indicates that increases in sympathetic nervous activity (SNA), and acclimatization
to high altitude (HA), may reduce endothelial function as assessed by brachial artery flow …

Key points We investigated the influence of arterial PCO2 (PaCO2) with and without
experimentally altered pH on cerebral blood flow (CBF) regulation at sea level and with …

Background In both humans and dogs the pulmonary vasculature is able to recruit large-
diameter anatomical intrapulmonary arteriovenous anastomoses (IPAVAs). In healthy …